Severe Organophosphate Poisoning with Acute Cholinergic Crisis, Intermediate Syndrome and Organophosphate Induced Long Term Ptosis.

Organophosphate compounds are the organic derivatives of Phosphorous containing acids and their clinical effects are due to action on neuromuscular junction and Autonomic Synapses. After exposure these agents cause acute and sub-acute manifestations depending on the type, severity of the agents and duration of presentation, like Acute Cholinergic Manifestations, Intermediate Syndrome (transient palsy) with Nicotinic features and Delayed Central Nervous System Complications. The patient reported here had severe Organophosphate Poisoning complicated by Intermediate Syndrome and Organophosphate Induced long term Ptosis. Highlighting such cases helps increase awareness of health care workers about these rare complications of a common problem. © Journal of the Association of Physicians of India 2011.