Simona Raimo1,2,3, Luigi Trojano2, Mariachiara Gaita2, Daniele Spitaleri4, Gabriella Santangelo5. 1. Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy. 2. Department of Psychology, University of Campania "Luigi Vanvitelli", Viale Ellittico, 31, 81100, Caserta, Italy. 3. IRCCS Fondazione Santa Lucia, Rome, Italy. 4. Neurology Unit "San Giuseppe Moscati", Hospital Avellino, Avellino, Italy. 5. Department of Psychology, University of Campania "Luigi Vanvitelli", Viale Ellittico, 31, 81100, Caserta, Italy. gabriella.santangelo@unicampania.it.
Abstract
BACKGROUND: Prospective memory (PM) deficits are often reported in multiple sclerosis (MS), but their relationship with neuropsychological characteristics and personality traits remains to be explored. OBJECTIVE: To systematically investigate both time-based and event-based PM abilities in a sample of MS without clinically relevant disability or global cognitive decline and to explore cognitive, neuropsychiatric characteristics and personality traits associated with PM deficits. METHODS: Thirty-three patients with MS and 33 healthy individuals were enrolled in the study. All participants underwent a standardized measure of PM to evaluate both time-based and event-based PM. Moreover, patients with MS completed the Brief Repeatable Battery to assess cognitive functioning, the Beck Depression Inventory-II and the Dimensional Apathy Scale to assess neuropsychiatric characteristics, and the NEO Personality Inventory-3 to assess personality traits. RESULTS: Individuals with MS demonstrated impaired time-based PM compared to healthy individuals. The regression analysis showed that poor performance in time-based PM was significantly related to lower extroversion and openness traits, whereas poor performance in event-based PM was significantly related to lower visuospatial memory abilities. CONCLUSIONS: Low levels of openness and extroversion traits are associated with a greater risk of developing time-based PM deficit. Therefore, personality assessment and behavioural interventions should be encouraged in MS clinical practice.
BACKGROUND: Prospective memory (PM) deficits are often reported in multiple sclerosis (MS), but their relationship with neuropsychological characteristics and personality traits remains to be explored. OBJECTIVE: To systematically investigate both time-based and event-based PM abilities in a sample of MS without clinically relevant disability or global cognitive decline and to explore cognitive, neuropsychiatric characteristics and personality traits associated with PM deficits. METHODS: Thirty-three patients with MS and 33 healthy individuals were enrolled in the study. All participants underwent a standardized measure of PM to evaluate both time-based and event-based PM. Moreover, patients with MS completed the Brief Repeatable Battery to assess cognitive functioning, the Beck Depression Inventory-II and the Dimensional Apathy Scale to assess neuropsychiatric characteristics, and the NEO Personality Inventory-3 to assess personality traits. RESULTS: Individuals with MS demonstrated impaired time-based PM compared to healthy individuals. The regression analysis showed that poor performance in time-based PM was significantly related to lower extroversion and openness traits, whereas poor performance in event-based PM was significantly related to lower visuospatial memory abilities. CONCLUSIONS: Low levels of openness and extroversion traits are associated with a greater risk of developing time-based PM deficit. Therefore, personality assessment and behavioural interventions should be encouraged in MS clinical practice.
Authors: Alberto Costa; Antonella Peppe; Silvia Zabberoni; Francesca Serafini; Francesco Barban; Francesco Scalici; Carlo Caltagirone; Giovanni Augusto Carlesimo Journal: Neuropsychology Date: 2015-02-02 Impact factor: 3.295
Authors: Avner Aronov; Laura A Rabin; Joshua Fogel; Susan Y Chi; Sarah J Kann; Nachama Abdelhak; Molly E Zimmerman Journal: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn Date: 2014-12-04
Authors: Giovanni A Carlesimo; Margherita di Paola; Lucia Fadda; Carlo Caltagirone; Alberto Costa Journal: Behav Neurol Date: 2014-03-09 Impact factor: 3.342