Literature DB >> 31310313

Safety and Tolerability of Clofazimine in a Cohort of Children With Odontogenic Mycobacterium abscessus Infection.

Felice C Adler-Shohet1, Jasjit Singh1, Delma Nieves1, Negar Ashouri1, M Tuan Tran2, M Cathy Flores1, Antonio Arrieta1.   

Abstract

Mycobacterium abscessus infections can be challenging to treat. Clofazimine has excellent in vitro activity against M abscessus, but reports of its use, particularly in children, have been limited. In this study, clofazimine was given to 27 children during an outbreak of odontogenic mycobacterial infections and seemed to be well tolerated as part of a multidrug regimen.
© The Author(s) 2019. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  child; clofazimine; disease outbreaks; nontuberculous mycobacteria; odontogenic infection

Mesh:

Substances:

Year:  2020        PMID: 31310313     DOI: 10.1093/jpids/piz049

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN: 2048-7193            Impact factor:   3.164


  2 in total

1.  Invasive Mycobacterium abscessus Outbreak at a Pediatric Dental Clinic.

Authors:  Jasjit Singh; Kathleen O'Donnell; Delma J Nieves; Felice C Adler-Shohet; Antonio C Arrieta; Negar Ashouri; Gurpreet Ahuja; Michele Cheung; W Nathan Holmes; Kevin Huoh; Lisa Tran; M Tuan Tran; Nguyen Pham; Matthew Zahn
Journal:  Open Forum Infect Dis       Date:  2021-04-15       Impact factor: 3.835

2.  Moxifloxacin Pharmacokinetics, Cardiac Safety, and Dosing for the Treatment of Rifampicin-Resistant Tuberculosis in Children.

Authors:  Kendra K Radtke; Anneke C Hesseling; J L Winckler; Heather R Draper; Belen P Solans; Stephanie Thee; Lubbe Wiesner; Louvina E van der Laan; Barend Fourie; James Nielsen; H Simon Schaaf; Radojka M Savic; Anthony J Garcia-Prats
Journal:  Clin Infect Dis       Date:  2022-04-28       Impact factor: 20.999

  2 in total

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