Literature DB >> 31308942

Comparison of early postoperative pain after partial tumour nephrectomy by flank, transabdominal or laparoscopic access.

Boris Hager1, Sereina A Herzog2, Barbara Hager3, Andreas Sandner-Kiesling3, Richard Zigeuner1, Karl Pummer1.   

Abstract

AIM: To explore whether the total pain experience differs after (partial) kidney tumour nephrectomies via flank, transabdominal or laparoscopic access.
MATERIALS AND METHODS: We analyzed retrospectively 107 patients with flank, 12 with transabdominal and 21 with laparoscopic interventions. For pain treatment, conventional analgesics (A) or intravenous patient-controlled analgesia (PCIA) or thoracic peridural analgesia (tPDA) were used. Self-reported pain was measured with a Visual Analogue Scale three times daily. The area under the curve (AUC) at rest (R) and during a standardized body movement (M) were calculated from the intervention till the end of the second T(0-2) and seventh postoperative day T(0-7), respectively.
RESULTS: The median AUC for T(0-2) at R was more intense for laparoscopy (13) than for flank incision (A, 9) and approximately the same during M. For flank incisions (A), the median AUC at R rises from 9 for T(0-2) to 22 for T(0-7) and at M the median AUC increases from 18 to 37. In contrast, laparoscopy did not cause further pain after the second postoperative day. Furthermore, with flank incision for T(0-2), at R, tPDA was superior to A (median AUC: 5 versus 9, p = 0.02) and at M again tPDA (median AUC: 12) had a better pain-control as A (18) or even as PCIA (19, p = 0.005).
CONCLUSION: Laparoscopic nephrectomies cause a relatively intense mean cumulative pain for T(0-2) and a subsequent absence of pain. However, flank incisions went on to increased pain levels until the seventh postoperative day with tPDA as most effective therapy.

Entities:  

Keywords:  Area under the curve; flank incision; laparoscopic nephrectomy; partial tumour nephrectomy; postoperative pain

Year:  2018        PMID: 31308942      PMCID: PMC6613070          DOI: 10.1177/2049463718808542

Source DB:  PubMed          Journal:  Br J Pain        ISSN: 2049-4637


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