Literature DB >> 31308604

Tx ™: An Approach and Philosophy to Advance Translation to Transformation.

Tabia Henry Akintobi1,2, Jammie Hopkins1,3, Kisha B Holden1,3,4, David Hefner1,5, Herman A Taylor6.   

Abstract

The translational science spectrum consists of phases or types of research, from discoveries that advance our understanding of the biological basis of health and disease to interventions that engage individuals and social systems toward improved population health. The health research system has widely acknowledged flaws that delay (or even deny) the fruits of research findings for the population and for chronically disadvantaged groups. Coined and patented at Morehouse School of Medicine (MSM), Tx ™;symbolizes an approach and scientific philosophy that intentionally promotes and supports the convergence of interdisciplinary approaches and scientists to stimulate exponential advances for the health of diverse communities. While the Tx ™ patent is new, this approach to research translation is embedded within the MSM tapestry with historically aligned research from the Translational Collaborative Center exemplars as well as newly funded scholars. Tx ™ scholarship is characterized by the five tenets and practices that ultimately culminate in the conduct of research with results that broaden the evidence-base through data-driven proof of impact on health equity in underserved or special populations. Tx ™ is a destination that is ever-evolving and responsive to the research, priority populations and partners through translational research and corresponding approaches that transform health, thereby advancing health equity.

Keywords:  Health Disparities; Health Equity; Implementation Science; Translational Research

Mesh:

Year:  2019        PMID: 31308604      PMCID: PMC6604776          DOI: 10.18865/ed.29.S2.349

Source DB:  PubMed          Journal:  Ethn Dis        ISSN: 1049-510X            Impact factor:   1.847


  11 in total

Review 1.  The value and challenges of participatory research: strengthening its practice.

Authors:  Margaret Cargo; Shawna L Mercer
Journal:  Annu Rev Public Health       Date:  2008       Impact factor: 21.981

2.  Community-based participatory research contributions to intervention research: the intersection of science and practice to improve health equity.

Authors:  Nina Wallerstein; Bonnie Duran
Journal:  Am J Public Health       Date:  2010-02-10       Impact factor: 9.308

3.  Defining translational research: implications for training.

Authors:  Doris McGartland Rubio; Ellie E Schoenbaum; Linda S Lee; David E Schteingart; Paul R Marantz; Karl E Anderson; Lauren Dewey Platt; Adriana Baez; Karin Esposito
Journal:  Acad Med       Date:  2010-03       Impact factor: 6.893

Review 4.  Using angiotensin converting enzyme inhibitors in African-American hypertensives: a new approach to treating hypertension and preventing target-organ damage.

Authors:  J M Flack; G A Mensah; C M Ferrario
Journal:  Curr Med Res Opin       Date:  2000       Impact factor: 2.580

5.  A trial of 3 interventions to promote colorectal cancer screening in African Americans.

Authors:  Daniel S Blumenthal; Selina A Smith; Charlye D Majett; Ernest Alema-Mensah
Journal:  Cancer       Date:  2010-02-15       Impact factor: 6.860

6.  Translation to practice of an intervention to promote colorectal cancer screening among African Americans.

Authors:  Selina Smith; Larry Johnson; Diane Wesley; Kim B Turner; Gail McCray; Joyce Sheats; Daniel Blumenthal
Journal:  Clin Transl Sci       Date:  2012-08-07       Impact factor: 4.689

7.  Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitor-Based Treatment on Cardiovascular Outcomes in Hypertensive Blacks Versus Whites.

Authors:  Gbenga Ogedegbe; Nirav R Shah; Christopher Phillips; Keith Goldfeld; Jason Roy; Yu Guo; Joyce Gyamfi; Christopher Torgersen; Louis Capponi; Sripal Bangalore
Journal:  J Am Coll Cardiol       Date:  2015-09-15       Impact factor: 24.094

Review 8.  Uncovering the benefits of participatory research: implications of a realist review for health research and practice.

Authors:  Justin Jagosh; Ann C Macaulay; Pierre Pluye; Jon Salsberg; Paula L Bush; Jim Henderson; Erin Sirett; Geoff Wong; Margaret Cargo; Carol P Herbert; Sarena D Seifer; Lawrence W Green; Trisha Greenhalgh
Journal:  Milbank Q       Date:  2012-06       Impact factor: 4.911

Review 9.  The answer is 17 years, what is the question: understanding time lags in translational research.

Authors:  Zoë Slote Morris; Steven Wooding; Jonathan Grant
Journal:  J R Soc Med       Date:  2011-12       Impact factor: 5.344

10.  Efficacy to effectiveness transition of an Educational Program to Increase Colorectal Cancer Screening (EPICS): study protocol of a cluster randomized controlled trial.

Authors:  Selina A Smith; Daniel S Blumenthal
Journal:  Implement Sci       Date:  2013-08-07       Impact factor: 7.327

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  1 in total

1.  Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research.

Authors:  Tabia Henry Akintobi; Payam Sheikhattari; Emma Shaffer; Christina L Evans; Kathryn L Braun; Angela U Sy; Bibiana Mancera; Adriana Campa; Stephania T Miller; Daniel Sarpong; Rhonda Holliday; Julio Jimenez-Chavez; Shafiq Khan; Cimona Hinton; Kimberly Sellars-Bates; Veronica Ajewole; Nicolette I Teufel-Shone; Juliet McMullin; Sandra Suther; K Sean Kimbro; Lorraine Taylor; Carmen M Velez Vega; Carla Williams; George Perry; Stephan Zuchner; Melissa Marzan Rodriguez; Paul B Tchounwou
Journal:  Int J Environ Res Public Health       Date:  2021-06-21       Impact factor: 3.390

  1 in total

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