Literature DB >> 31308180

Rare case of parathyroid gland sarcoidosis presenting with hypercalcaemia.

Biplab Kumar Saha1, Stacey L Burns2, Llewellyn A Foulke3, Marc A Judson1.   

Abstract

Sarcoidosis of the parathyroid gland is a rare occurrence. Parathyroid sarcoidosis is usually associated with parathyroid adenomas, and, therefore, hypercalcaemia is a common presentation of this entity. We present a case of parathyroid sarcoidosis and review the world literature regarding this rare condition. A woman with a history of diffuse large B cell lymphoma underwent a surveillance positron emission tomography scan that showed increased fluorodeoxyglucose uptake in multiple thoracic and abdominal lymph nodes and in a left upper extremity soft tissue mass. Biopsy of the soft tissue mass showed non-caseating granulomas consistent with sarcoidosis. Blood work showed a serum calcium of 11.1 mg/dL with an intact serum parathyroid hormone of 92 pg/dL. Primary hyperparathyroidism was suspected. A neck ultrasound and sestamibi parathyroid scintigraphy demonstrated a parathyroid nodule. She underwent surgical resection, and the histopathology revealed a parathyroid adenoma and non-caseating granulomata consistent with a diagnosis of sarcoidosis. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  calcium and bone; ear, nose and throat/otolaryngology; endocrine system; respiratory system

Mesh:

Year:  2019        PMID: 31308180      PMCID: PMC6663241          DOI: 10.1136/bcr-2019-230598

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  How are cancer and connective tissue diseases related to sarcoidosis?

Authors:  Amit Chopra; Marc A Judson
Journal:  Curr Opin Pulm Med       Date:  2015-09       Impact factor: 3.155

2.  Calcium metabolism in sarcoidosis and its clinical implications.

Authors:  M Conron; C Young; H L Beynon
Journal:  Rheumatology (Oxford)       Date:  2000-07       Impact factor: 7.580

3.  Sarcoidosis, hypercalcemia and primary hyperparathyroidism. The vicissitudes of diagnosis.

Authors:  V G Schweitzer; N W Thompson; K A Clark; R H Nishiyama; S T Bigos
Journal:  Am J Surg       Date:  1981-10       Impact factor: 2.565

4.  Sarcoid granulomas in the parathyroid gland - a case of dual pathology: hypercalcaemia due to a parathyroid adenoma and coexistent sarcoidosis with granulomas located within the parathyroid adenoma and thyroid gland.

Authors:  Anjali Balasanthiran; Belinda Sandler; Kwamena Amonoo-Kuofi; Rajiv Swamy; Sunil Kaniyur; Felicity Kaplan
Journal:  Endocr J       Date:  2010-06-15       Impact factor: 2.349

5.  Evidence that increased circulating 1 alpha, 25-dihydroxyvitamin D is the probable cause for abnormal calcium metabolism in sarcoidosis.

Authors:  N H Bell; P H Stern; E Pantzer; T K Sinha; H F DeLuca
Journal:  J Clin Invest       Date:  1979-07       Impact factor: 14.808

6.  Cystic parathyroid adenoma with coexistent sarcoid granulomas.

Authors:  K Taguchi; K Makimoto; S Nagai; M Kitaichi; T Izumi; H Yamabe
Journal:  Arch Otorhinolaryngol       Date:  1987

7.  Parathyroid adenoma with coexistent sarcoid granulomas. A hypercalcemic patient.

Authors:  R G Robinson; D M Kerwin; E Tsou
Journal:  Arch Intern Med       Date:  1980-11

8.  Unusual recurrence of hypercalcemia due to concurrent parathyroid adenoma and parathyroid sarcoidosis with lymph node involvement.

Authors:  Leila Chaychi; Sushela Chaidarun; Allan Golding; William B Kinlaw; Vincent Memoli; Alan Siegel
Journal:  Endocr Pract       Date:  2010 May-Jun       Impact factor: 3.443

9.  1, 25-dihydroxycholecalciferol in the pathogenesis of the hypercalcaemia of sarcoidosis.

Authors:  S E Papapoulos; T L Clemens; L J Fraher; I G Lewin; L M Sandler; J L O'Riordan
Journal:  Lancet       Date:  1979-03-24       Impact factor: 79.321

  9 in total
  1 in total

Review 1.  Osseous manifestations of sarcoidosis.

Authors:  Eugeniusz Józef Kucharz
Journal:  Reumatologia       Date:  2020-04-30
  1 in total

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