Literature DB >> 31308110

Deprescribing in palliative care.

Jo Thompson1.   

Abstract

The use of multiple medications is common in palliative care, putting patients at risk of adverse events and a high tablet burden. Deprescribing is the process of reviewing and stopping potentially inappropriate medications in order to improve quality of life. Barriers to deprescribing exist meaning many patients will take multiple medications despite being in the final months of life. The OncPal deprescribing guideline is a useful tool to support the process for patients with a limited life expectancy. There is evidence for the safety of stopping certain medications, particularly those aimed at primary prevention. A systematic process of reviewing individual medications and their appropriateness is recommended. © Royal College of Physicians 2019. All rights reserved.

Entities:  

Keywords:  OncPal deprescribing guideline; Polypharmacy; deprescribing; medication review

Year:  2019        PMID: 31308110      PMCID: PMC6752237          DOI: 10.7861/clinmedicine.19-4-311

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  17 in total

1.  Reconsidering medication appropriateness for patients late in life.

Authors:  Holly M Holmes; Déon Cox Hayley; G Caleb Alexander; Greg A Sachs
Journal:  Arch Intern Med       Date:  2006-03-27

2.  Use of unnecessary medications by patients with advanced cancer: cross-sectional survey.

Authors:  Angelo Fede; Michele Miranda; Daniella Antonangelo; Ligia Trevizan; Henrique Schaffhausser; Bruno Hamermesz; Camile Zimmermann; Auro Del Giglio; Rachel P Riechelmann
Journal:  Support Care Cancer       Date:  2010-07-21       Impact factor: 3.603

3.  Reducing inappropriate polypharmacy: the process of deprescribing.

Authors:  Ian A Scott; Sarah N Hilmer; Emily Reeve; Kathleen Potter; David Le Couteur; Deborah Rigby; Danijela Gnjidic; Christopher B Del Mar; Elizabeth E Roughead; Amy Page; Jesse Jansen; Jennifer H Martin
Journal:  JAMA Intern Med       Date:  2015-05       Impact factor: 21.873

4.  Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial.

Authors:  Jean S Kutner; Patrick J Blatchford; Donald H Taylor; Christine S Ritchie; Janet H Bull; Diane L Fairclough; Laura C Hanson; Thomas W LeBlanc; Greg P Samsa; Steven Wolf; Noreen M Aziz; David C Currow; Betty Ferrell; Nina Wagner-Johnston; S Yousuf Zafar; James F Cleary; Sandesh Dev; Patricia S Goode; Arif H Kamal; Cordt Kassner; Elizabeth A Kvale; Janelle G McCallum; Adeboye B Ogunseitan; Steven Z Pantilat; Russell K Portenoy; Maryjo Prince-Paul; Jeff A Sloan; Keith M Swetz; Charles F Von Gunten; Amy P Abernethy
Journal:  JAMA Intern Med       Date:  2015-05       Impact factor: 21.873

Review 5.  Reducing potentially inappropriate medications in palliative cancer patients: evidence to support deprescribing approaches.

Authors:  Julian Lindsay; Michael Dooley; Jennifer Martin; Michael Fay; Alison Kearney; Michael Barras
Journal:  Support Care Cancer       Date:  2013-12-21       Impact factor: 3.603

6.  Commonly prescribed medications in a population of hospice patients.

Authors:  Leah Sera; Mary Lynn McPherson; Holly M Holmes
Journal:  Am J Hosp Palliat Care       Date:  2013-02-12       Impact factor: 2.500

7.  The development and evaluation of an oncological palliative care deprescribing guideline: the 'OncPal deprescribing guideline'.

Authors:  Julian Lindsay; Michael Dooley; Jennifer Martin; Michael Fay; Alison Kearney; Mohsina Khatun; Michael Barras
Journal:  Support Care Cancer       Date:  2014-07-01       Impact factor: 3.603

8.  Polypharmacy and drug omissions across hospices in Northern Ireland.

Authors:  Emma Lundy; Damien McMullan; Patrick McShane; Matthew Williams; Max Watson; Clare White
Journal:  J Palliat Med       Date:  2013-10-16       Impact factor: 2.947

9.  Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process.

Authors:  Emily Reeve; Sepehr Shakib; Ivanka Hendrix; Michael S Roberts; Michael D Wiese
Journal:  Br J Clin Pharmacol       Date:  2014-10       Impact factor: 4.335

10.  Preventive medication use among persons with limited life expectancy.

Authors:  André R Maddison; Judith Fisher; Grace Johnston
Journal:  Prog Palliat Care       Date:  2011-01
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  5 in total

1.  Nudge nudge, wink wink.

Authors:  Anton Emmanuel
Journal:  Clin Med (Lond)       Date:  2019-07       Impact factor: 2.659

Review 2.  Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review.

Authors:  Dinushika Mohottige; Harold J Manley; Rasheeda K Hall
Journal:  Kidney360       Date:  2021-07-09

Review 3.  Palliative care in liver disease: what does good look like?

Authors:  Hazel Woodland; Ben Hudson; Karen Forbes; Anne McCune; Mark Wright
Journal:  Frontline Gastroenterol       Date:  2019-09-10

4.  Understanding the Potential for Pharmacy Expertise in Palliative Care: The Value of Stakeholder Engagement in a Theoretically Driven Mapping Process for Research.

Authors:  Joseph Elyan; Sally-Anne Francis; Sarah Yardley
Journal:  Pharmacy (Basel)       Date:  2021-11-26

5.  Deprescribing in Hospice Patients: Discontinuing Aspirin, Multivitamins, and Statins.

Authors:  Cari E Low; Daniel E Sanchez Pellecer; Wil L Santivasi; Virginia H Thompson; Theresa Elwood; Ashly J Davidson; Julie A Tlusty; Molly A Feely; Cory Ingram
Journal:  Mayo Clin Proc Innov Qual Outcomes       Date:  2021-07-24
  5 in total

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