Literature DB >> 3130792

Differential expression of "Fe-repressible" and "growth-rate-sensitive" proteins in Neisseria meningitidis and Neisseria gonorrhoeae.

J P van Putten1, M T Linders, J F Weel, J T Poolman.   

Abstract

By varying growth conditions, we were able to differentiate (SDS-PAGE) between true "Fe-repressible" proteins and "growth-rate-sensitive" proteins (GSP's) (60-110 Kd) in outer membranes of iron-starved meningococci and gonococci. Immunological characterization with monoclonal antibodies raised against the GSP's revealed (GIRA) crossreactivity between different GSP's. On the basis of common epitopes, two groups of proteins could be distinguished. Immuno-electron-microscopy showed that proteins of both groups were exposed at the cell surface.

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Year:  1987        PMID: 3130792     DOI: 10.1007/bf00415517

Source DB:  PubMed          Journal:  Antonie Van Leeuwenhoek        ISSN: 0003-6072            Impact factor:   2.271


  10 in total

1.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

2.  Monoclonal antibody activity against native and denatured forms of gonococcal outer membrane proteins as detected within ultrathin, longitudinal slices of polyacrylamide gels.

Authors:  J T Poolman; T M Buchanan
Journal:  J Immunol Methods       Date:  1984-12-31       Impact factor: 2.303

Review 3.  Microbial envelope proteins related to iron.

Authors:  J B Neilands
Journal:  Annu Rev Microbiol       Date:  1982       Impact factor: 15.500

4.  Vibrio cholerae expresses iron-regulated outer membrane proteins in vivo.

Authors:  C V Sciortino; R A Finkelstein
Journal:  Infect Immun       Date:  1983-12       Impact factor: 3.441

5.  Distribution of an antigenically related iron-regulated protein among the Neisseria spp.

Authors:  T A Mietzner; R C Barnes; Y A JeanLouis; W M Shafer; S A Morse
Journal:  Infect Immun       Date:  1986-01       Impact factor: 3.441

6.  Increased virulence of Neisseria meningitidis after in vitro iron-limited growth at low pH.

Authors:  D Brener; I W DeVoe; B E Holbein
Journal:  Infect Immun       Date:  1981-07       Impact factor: 3.441

7.  Response of Neisseria gonorrhoeae to iron limitation: alterations in expression of membrane proteins without apparent siderophore production.

Authors:  S E West; P F Sparling
Journal:  Infect Immun       Date:  1985-02       Impact factor: 3.441

8.  Serological classification of Neisseria gonorrhoeae with monoclonal antibodies.

Authors:  M R Tam; T M Buchanan; E G Sandström; K K Holmes; J S Knapp; A W Siadak; R C Nowinski
Journal:  Infect Immun       Date:  1982-06       Impact factor: 3.441

9.  Sizing of protein A-colloidal gold probes for immunoelectron microscopy.

Authors:  J W Slot; H J Geuze
Journal:  J Cell Biol       Date:  1981-08       Impact factor: 10.539

10.  The serological classification of Neisseria gonorrhoeae. I. Isolation of the outer membrane complex responsible for serotypic specificity.

Authors:  K H Johnston; K K Holmes; E C Gotschlich
Journal:  J Exp Med       Date:  1976-04-01       Impact factor: 14.307

  10 in total
  1 in total

Review 1.  Iron acquisition and the pathogenesis of meningococcal and gonococcal disease.

Authors:  J P van Putten
Journal:  Med Microbiol Immunol       Date:  1990       Impact factor: 3.402

  1 in total

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