Literature DB >> 31304991

The prospects for recombinant proteins from transgenic animals: A few successes along with the advent of new technologies increase the allure of transgenic animals for the production of therapeutic human proteins.

Philip Hunter1.   

Abstract

The use of GM animals to produce human recombinant therapeutic proteins has progressed only slowly. But recent successes and new technologies could speed up development.
© 2019 The Author.

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Year:  2019        PMID： 31304991      PMCID： PMC6680168          DOI： 10.15252/embr.201948757

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


  7 in total

1.  [Insertion of Multiple Artificial Introns of Universal Design into cDNA during Minigene Construction Assures Correct Transgene Splicing].

Authors:  M V Shepelev; M V Tikhonov; S V Kalinichenko; I V Korobko
Journal:  Mol Biol (Mosk)       Date:  2018 May-Jun

Review 2.  How introns enhance gene expression.

Authors:  Orit Shaul
Journal:  Int J Biochem Cell Biol       Date:  2017-07-01       Impact factor: 5.085

Review 3.  A fast track influenza virus vaccine produced in insect cells.

Authors:  Manon M J Cox; Yoshifumi Hashimoto
Journal:  J Invertebr Pathol       Date:  2011-07       Impact factor: 2.841

4.  Production of human beta interferon in insect cells infected with a baculovirus expression vector.

Authors:  G E Smith; M D Summers; M J Fraser
Journal:  Mol Cell Biol       Date:  1983-12       Impact factor: 4.272

5.  A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency.

Authors:  Barbara K Burton; Manisha Balwani; François Feillet; Ivo Barić; T Andrew Burrow; Carmen Camarena Grande; Mahmut Coker; Alejandra Consuelo-Sánchez; Patrick Deegan; Maja Di Rocco; Gregory M Enns; Richard Erbe; Fatih Ezgu; Can Ficicioglu; Katryn N Furuya; John Kane; Christina Laukaitis; Eugen Mengel; Edward G Neilan; Scott Nightingale; Heidi Peters; Maurizio Scarpa; K Otfried Schwab; Vratislav Smolka; Vassili Valayannopoulos; Marnie Wood; Zachary Goodman; Yijun Yang; Stephen Eckert; Sandra Rojas-Caro; Anthony G Quinn
Journal:  N Engl J Med       Date:  2015-09-10       Impact factor: 91.245

6.  Use of transgenic animals in biotechnology: prospects and problems.

Authors:  O G Maksimenko; A V Deykin; Yu M Khodarovich; P G Georgiev
Journal:  Acta Naturae       Date:  2013-01       Impact factor: 1.845

7.  A chicken bioreactor for efficient production of functional cytokines.

Authors:  Lissa R Herron; Clare Pridans; Matthew L Turnbull; Nikki Smith; Simon Lillico; Adrian Sherman; Hazel J Gilhooley; Martin Wear; Dominic Kurian; Grigorios Papadakos; Paul Digard; David A Hume; Andrew C Gill; Helen M Sang
Journal:  BMC Biotechnol       Date:  2018-12-29       Impact factor: 2.563
  7 in total

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