Literature DB >> 31304241

Prevalence of spontaneous dyskinesia in first episode, drug naive schizophrenia, and its relation to the positive and negative symptoms of schizophrenia.

Samrat Singh Bhandari1, Dipesh Bhagabati2.   

Abstract

AIMS AND
OBJECTIVES: This study aims to assess the prevalence of abnormal involuntary movement in never medicated patients with schizophrenia and to find its relation with demographic variables, and with the positive and negative symptoms of schizophrenia; this study also aims to assess the topography of the dyskinesia.
METHODOLOGY: Socio-demographic data of 100 consecutively selected patients who fulfilled the ICD-10 Diagnostic Criteria for Research were collected in a 12-month period. These patients were rated with the Positive And Negative Syndrome Scale (PANSS) and Abnormal Involuntary Movement Scale (AIMS). Patients were labeled as having spontaneous dyskinesia if they fulfilled the criteria of Schooler and Kane which needs a score of two (mild) in at least two areas or score of three (moderate) or four (severe) in one area.
RESULTS: Fifty two per cent of the study samples were male and 48% were female with mean age of 30.72 years with standard deviation of 8.7 years. Sixteen per cent of the patients had dyskinesia when examined with AIMS. However, only 14% fulfilled the Schooler and Kane's criteria for spontaneous dyskinesia. A strong correlation was found between the presence of dyskinesia and negative symptoms of schizophrenia. 57.1% of these 14 patients had dyskinesia located in their oral and facial region. Seventy one per cent of these patients with dyskinesia had no awareness of their involuntary movements.
CONCLUSIONS: Spontaneous dyskinesia, negative symptoms, and lack of awareness of the abnormal involuntary movement can be taken as one of the presenting symptoms of schizophrenia.

Entities:  

Keywords:  Abnormal Involuntary Movement; Dyskinesia; Positive and Negative Symptoms; Schizophrenia

Year:  2016        PMID: 31304241      PMCID: PMC6625795          DOI: 10.5958/2394-2061.2017.00005.2

Source DB:  PubMed          Journal:  Open J Psychiatry Allied Sci        ISSN: 2394-2053


  27 in total

1.  Correlates of positive and negative schizophrenic syndromes in Nigerian patients.

Authors:  O Gureje
Journal:  Br J Psychiatry       Date:  1989-11       Impact factor: 9.319

2.  Not all that moves is tardive dyskinesia.

Authors:  V Khot; R J Wyatt
Journal:  Am J Psychiatry       Date:  1991-05       Impact factor: 18.112

3.  Relationship of awareness of dyskinesia in schizophrenia to insight into mental illness.

Authors:  C Arango; H Adami; J D Sherr; G K Thaker; W T Carpenter
Journal:  Am J Psychiatry       Date:  1999-07       Impact factor: 18.112

4.  The significance of subtyping tardive dyskinesia: a study of prevalence and associated factors.

Authors:  O Gureje
Journal:  Psychol Med       Date:  1989-02       Impact factor: 7.723

Review 5.  Motor deficits and schizophrenia: the evidence from neuroleptic-naïve patients and populations at risk.

Authors:  A L Wolff; G A O'Driscoll
Journal:  J Psychiatry Neurosci       Date:  1999-09       Impact factor: 6.186

6.  The motor disorders of severe psychiatric illness: a conflict of paradigms.

Authors:  D Rogers
Journal:  Br J Psychiatry       Date:  1985-09       Impact factor: 9.319

7.  The impact of neuroleptic medication on tardive dyskinesia: a meta-analysis of published studies.

Authors:  H Morgenstern; W M Glazer; D Niedzwiecki; P Nourjah
Journal:  Am J Public Health       Date:  1987-06       Impact factor: 9.308

8.  Clinical and familial correlates of tardive dyskinesia in India and Israel.

Authors:  T Bhatia; M R Sabeeha; V Shriharsh; K Garg; R H Segman; H L Uriel; R Strous; V L Nimgaonkar; L Bernard; S N Deshpande
Journal:  J Postgrad Med       Date:  2004 Jul-Sep       Impact factor: 1.476

9.  Subjective awareness of abnormal involuntary movements in chronic schizophrenic patients.

Authors:  G Caracci; S Mukherjee; S D Roth; P Decina
Journal:  Am J Psychiatry       Date:  1990-03       Impact factor: 18.112

10.  Spontaneous dyskinesia and parkinsonism in never-medicated, chronically ill patients with schizophrenia: 18-month follow-up.

Authors:  R G McCreadie; R Padmavati; R Thara; T N Srinivasan
Journal:  Br J Psychiatry       Date:  2002-08       Impact factor: 9.319

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