Literature DB >> 3130273

Pure red cell aplasia. Stable complete remission following antilymphocyte globulin administration.

P Jacobs1, L Wood.   

Abstract

A 25-yr-old woman with idiopathic pure red cell aplasia achieved complete remission following a single 5-day course of antilymphocyte globulin at a dose of 50 mg/kg daily by intravenous injection as initial and sole therapy. Apart from transient arthralgia and asymptomatic thrombocytopenia there were no side effects. At 2 yr, the patient has normal peripheral blood, bone marrow and in vitro culture studies. This approach offers an alternative to conventional immunosuppressive therapy where there is evidence of an underlying immune disorder.

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Year:  1988        PMID: 3130273     DOI: 10.1111/j.1600-0609.1988.tb00194.x

Source DB:  PubMed          Journal:  Eur J Haematol        ISSN: 0902-4441            Impact factor:   2.997


  2 in total

Review 1.  Pure red cell aplasia: review of treatment and proposal for a treatment strategy.

Authors:  A Raghavachar
Journal:  Blut       Date:  1990 Aug-Sep

Review 2.  Anti Thymocyte Globulin-Based Treatment for Acquired Bone Marrow Failure in Adults.

Authors:  Jennifer M-L Tjon; Saskia M C Langemeijer; Constantijn J M Halkes
Journal:  Cells       Date:  2021-10-27       Impact factor: 6.600

  2 in total

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