Literature DB >> 31301042

Case report of primary dural lymphoma mimicking a cerebellar meningioma and brief review of literature.

Salvatore D'Oria1, Mariagrazia Dibenedetto2, Eleonora Squillante3, Rosa Maria Bona4, Carlo Somma2, Umberto Godano2.   

Abstract

Primary dural lymphoma (PDL) is an extremely rare subtype of primary central nervous system lymphoma arising from the dura mater in absence of systemic disease. The most common histological type is the low-grade marginal zone lymphoma, whereas high-grade lymphomas are unusual. We present a case of primary diffuse large B-cell lymphoma, presenting as PDL in the posterior fossa, originating from the dura mater of the petrous bone covering the surface of the left cerebellum, a location not previously described. A 65-year-old woman presented with sudden onset of severe dizziness was admitted in otolaryngology department then transferred to neurosurgery ward. CT scan revealed a large lesion involving left cerebellum, subsequent MRI of the brain demonstrated an enhancing mass suggestive for petrous bone meningioma. The tumor was excised, and the histopathological examination unexpectedly revealed a diffuse large B-cell lymphoma. The patient received postoperative chemoradiotherapy. 20 months after surgery a good outcome was registered. Due to the rarity of primary dural lymphomas no standard treatment is available, however, gross total or subtotal resection followed by adjuvant therapy seems to be a good choice to manage the pathology.

Entities:  

Keywords:  Cerebellum; Dural lymphoma; Neurosurgery; Petrous bone

Year:  2019        PMID: 31301042     DOI: 10.1007/s13760-019-01188-2

Source DB:  PubMed          Journal:  Acta Neurol Belg        ISSN: 0300-9009            Impact factor:   2.396


  1 in total

1.  Intracranial malignant B-cell lymphoma of the dura.

Authors:  D Freudenstein; A Bornemann; U Ernemann; R Boldt; F Duffner
Journal:  Clin Neuropathol       Date:  2000 Jan-Feb       Impact factor: 1.368

  1 in total

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