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Literature DB >> 3129990

Pyrazinamide is not effective against intracellularly growing Mycobacterium tuberculosis.

N Rastogi, M C Potar, H L David.

Abstract

Entities: Chemical Species

Mesh：

Substances：
Pyrazinamide

Year: 1988 PMID： 3129990 PMCID： PMC172157 DOI： 10.1128/AAC.32.2.287

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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6 in total

1. The intracellular activation of pyrazinamide and nicotinamide.

Authors: G B MACKANESS
Journal: Am Rev Tuberc Date: 1956-11

2. Determination of drug susceptibility of mycobacteria to pyrazinamide in 7H10 agar.

Authors: K D Stottmeier; R E Beam; G P Kubica
Journal: Am Rev Respir Dis Date: 1967-11

3. Killing of macrophage-ingested mycobacteria by rifampicin, pyrazinamide, and pyrazinoic acid alone and in combination.

Authors: N A Carlone; G Acocella; A M Cuffini; M Forno-Pizzoglio
Journal: Am Rev Respir Dis Date: 1985-12

4. The penetration of rifampicin, pyrazinamide, and pyrazinoic acid into mouse macrophages.

Authors: G Acocella; N A Carlone; A M Cuffini; G Cavallo
Journal: Am Rev Respir Dis Date: 1985-12

5. Inhibition by pyrazinamide of tubercle bacilli within cultured human macrophages.

Authors: A J Crowle; J A Sbarbaro; M H May
Journal: Am Rev Respir Dis Date: 1986-11

6. Structure of the cell envelope of Mycobacterium avium.

Authors: H L David; N Rastogi; S Clavel-Sérès; F Clément; M F Thorel
Journal: Zentralbl Bakteriol Mikrobiol Hyg A Date: 1987-04

6 in total

1. Extracellular and intracellular activities of clarithromycin used alone and in association with ethambutol and rifampin against Mycobacterium avium complex.

Authors: N Rastogi; V Labrousse
Journal: Antimicrob Agents Chemother Date: 1991-03 Impact factor: 5.191

2. High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis.

Authors: Mayra Silva-Miranda; Euloge Ekaza; Adrien Breiman; Karim Asehnoune; David Barros-Aguirre; Kevin Pethe; Fanny Ewann; Priscille Brodin; Lluís Ballell-Pages; Frédéric Altare
Journal: Antimicrob Agents Chemother Date: 2014-10-27 Impact factor: 5.191

Pyrazinamide is not effective against intracellularly growing Mycobacterium tuberculosis.

1. The intracellular activation of pyrazinamide and nicotinamide.

2. Determination of drug susceptibility of mycobacteria to pyrazinamide in 7H10 agar.

3. Killing of macrophage-ingested mycobacteria by rifampicin, pyrazinamide, and pyrazinoic acid alone and in combination.

4. The penetration of rifampicin, pyrazinamide, and pyrazinoic acid into mouse macrophages.

5. Inhibition by pyrazinamide of tubercle bacilli within cultured human macrophages.

6. Structure of the cell envelope of Mycobacterium avium.

1. Extracellular and intracellular activities of clarithromycin used alone and in association with ethambutol and rifampin against Mycobacterium avium complex.

2. High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis.

Review 3. Targeting Phenotypically Tolerant Mycobacterium tuberculosis.

4. Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection.

5. The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB.

Review 6. Impact of the host environment on the antitubercular action of pyrazinamide.