Trine Munk Jensen1, Sofie Bjerre Milling Eriksen2, Jane Sedum Larsen3, Mette Aadahl4, Signe Sætre Rasmussen5, Louise Bockhoff Olesen2, Thomas Rehling2, Stig Molsted6. 1. Department of Clinical Research, Nordsjællands Hospital, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. 2. Department of Physiotherapy, Nordsjællands Hospital, Denmark. 3. Louiselund, Hørsholm Kommune, Denmark. 4. Centre for Clinical Research and Prevention, Frederiksberg-Bispebjerg Hospital, Copenhagen, Denmark; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. 5. Steno Diabetes Center Copenhagen, Denmark. 6. Department of Clinical Research, Nordsjællands Hospital, Denmark. Electronic address: stimo@regionh.dk.
Abstract
AIMS: To investigate the effect of exercise training on musculoskeletal pain in patients with type 2 diabetes. METHODS: The intervention was exercise twice weekly for 12 weeks. The primary outcome was musculoskeletal pain assessed using a 0-10 Numeric Rating Scale (NRS) in 11 body sites. Secondary outcomes were use of analgesics, glycaemic control and body weight. RESULTS: The participants (n = 69) were 66 ± 10 years old, 38 were men and 50 completed the intervention. Pain in the limbs was more frequently reported by the participants compared to a matched general population (80.9% vs 65.3%, p = 0.007). The participants who had any pain at baseline (NRS > 0) and severe pain (NRS > 3) reported significantly decreased pain in the feet, calf muscles, knees, thighs, hips, lower back and arms after the training period. Use of analgesics was unchanged, HbA1c (mmol/mol) decreased from 60 ± 15 to 54 ± 11, p < 0.001 and body weight (kg) decreased from 100.5 ± 19.1 to 98.6 ± 17.7, p = 0.005. CONCLUSIONS: The participants with type 2 diabetes reported more frequent pain than a matched general population. The training intervention was associated with reduced musculoskeletal pain. Reduced pain may together with a positive impact on glycaemic control be an important motivational factor in patients with type 2 diabetes to perform exercise training.
RCT Entities:
AIMS: To investigate the effect of exercise training on musculoskeletal pain in patients with type 2 diabetes. METHODS: The intervention was exercise twice weekly for 12 weeks. The primary outcome was musculoskeletal pain assessed using a 0-10 Numeric Rating Scale (NRS) in 11 body sites. Secondary outcomes were use of analgesics, glycaemic control and body weight. RESULTS: The participants (n = 69) were 66 ± 10 years old, 38 were men and 50 completed the intervention. Pain in the limbs was more frequently reported by the participants compared to a matched general population (80.9% vs 65.3%, p = 0.007). The participants who had any pain at baseline (NRS > 0) and severe pain (NRS > 3) reported significantly decreased pain in the feet, calf muscles, knees, thighs, hips, lower back and arms after the training period. Use of analgesics was unchanged, HbA1c (mmol/mol) decreased from 60 ± 15 to 54 ± 11, p < 0.001 and body weight (kg) decreased from 100.5 ± 19.1 to 98.6 ± 17.7, p = 0.005. CONCLUSIONS: The participants with type 2 diabetes reported more frequent pain than a matched general population. The training intervention was associated with reduced musculoskeletal pain. Reduced pain may together with a positive impact on glycaemic control be an important motivational factor in patients with type 2 diabetes to perform exercise training.
Authors: Stig Molsted; Lasse Kusk; Søren Mingon Esbensen; Thomas Martin Mohr; Malene Bang Vind; Camilla Hess; Thomas Bandholm; Morten Tange Kristensen; Cornelie Mølsted Flege; Peter Lommer Kristensen Journal: Int J Environ Res Public Health Date: 2022-01-18 Impact factor: 3.390
Authors: Mary K Hastings; Hyo-Jung Jeong; Christopher J Sorensen; Jennifer A Zellers; Ling Chen; Kathryn L Bohnert; Darrah Snozek; Michael J Mueller Journal: Foot (Edinb) Date: 2020-03-30