Literature DB >> 3129785

Identification and characterization of a neuron-specific nuclear antigen in Drosophila.

E Bier1, L Ackerman, S Barbel, L Jan, Y N Jan.   

Abstract

An antigen found only in neuronal nuclei of Drosophila melanogaster is revealed by staining with a monoclonal antibody (Mab44C11). This antigen appears early in development, before neurons show any other signs of antigenic or morphologic differentiation, and persists throughout development. This nuclear staining permits reliable detection of neurons in developmental studies of wild-type and mutant flies. Protein immunoblot analyses and immune precipitation experiments show that the neuronal nuclear antigen is a 50-kilodalton polypeptide.

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Year:  1988        PMID： 3129785     DOI： 10.1126/science.3129785

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  21 in total

1.  Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesis.

Authors:  L Li; H Vaessin
Journal:  Genes Dev       Date:  2000-01-15       Impact factor: 11.361

2.  Spatial and temporal expression of the period and timeless genes in the developing nervous system of Drosophila: newly identified pacemaker candidates and novel features of clock gene product cycling.

Authors:  M Kaneko; C Helfrich-Förster; J C Hall
Journal:  J Neurosci       Date:  1997-09-01       Impact factor: 6.167

Review 3.  RNA protein interaction in neurons.

Authors:  Robert B Darnell
Journal:  Annu Rev Neurosci       Date:  2013-05-20       Impact factor: 12.449

4.  Identification and characterization of autosomal genes that interact with glass in the developing Drosophila eye.

Authors:  C Ma; H Liu; Y Zhou; K Moses
Journal:  Genetics       Date:  1996-04       Impact factor: 4.562

5.  The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string.

Authors:  B A Edgar; P H O'Farrell
Journal:  Cell       Date:  1990-08-10       Impact factor: 41.582

6.  Second-site modifiers of the split mutation of Notch define genes involved in neurogenesis in Drosophila melanogaster.

Authors:  Michael Brand; José A Campos-Ortega
Journal:  Rouxs Arch Dev Biol       Date:  1990-02

7.  Second-site modifiers of the Delta wing phenotype in Drosophila melanogaster.

Authors:  Thomas Klein; Jose A Campos-Ortega
Journal:  Rouxs Arch Dev Biol       Date:  1992-12

8.  Identification of a Drosophila G protein alpha subunit (dGq alpha-3) expressed in chemosensory cells and central neurons.

Authors:  S Talluri; A Bhatt; D P Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-05       Impact factor: 11.205

9.  A conserved family of elav-like genes in vertebrates.

Authors:  P J Good
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205

Review 10.  Studying polyglutamine diseases in Drosophila.

Authors:  Zhen Xu; Antonio Joel Tito; Yan-Ning Rui; Sheng Zhang
Journal:  Exp Neurol       Date:  2015-08-06       Impact factor: 5.330
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