Literature DB >> 31297825

Bayesian consensus-based sample size criteria for binomial proportions.

Lawrence Joseph1, Patrick Bélisle2.   

Abstract

Many sample size criteria exist. These include power calculations and methods based on confidence interval widths from a frequentist viewpoint, and Bayesian methods based on credible interval widths or decision theory. Bayesian methods account for the inherent uncertainty of inputs to sample size calculations through the use of prior information rather than the point estimates typically used by frequentist methods. However, the choice of prior density can be problematic because there will almost always be different appreciations of the past evidence. Such differences can be accommodated a priori by robust methods for Bayesian design, for example, using mixtures or ϵ-contaminated priors. This would then ensure that the prior class includes divergent opinions. However, one may prefer to report several posterior densities arising from a "community of priors," which cover the range of plausible prior densities, rather than forming a single class of priors. To date, however, there are no corresponding sample size methods that specifically account for a community of prior densities in the sense of ensuring a large-enough sample size for the data to sufficiently overwhelm the priors to ensure consensus across widely divergent prior views. In this paper, we develop methods that account for the variability in prior opinions by providing the sample size required to induce posterior agreement to a prespecified degree. Prototypic examples to one- and two-sample binomial outcomes are included. We compare sample sizes from criteria that consider a family of priors to those that would result from previous interval-based Bayesian criteria.
© 2019 John Wiley & Sons, Ltd.

Keywords:  Bayesian methods; binomial proportions; clinical trials; credible intervals; prior specification; sample size determination; study design

Year:  2019        PMID: 31297825     DOI: 10.1002/sim.8316

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  1 in total

1.  Sample Size Requirements for Calibrated Approximate Credible Intervals for Proportions in Clinical Trials.

Authors:  Fulvio De Santis; Stefania Gubbiotti
Journal:  Int J Environ Res Public Health       Date:  2021-01-12       Impact factor: 3.390

  1 in total

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