Literature DB >> 31297685

Symptoms and QOL in breast cancer patients receiving hormone therapy in Japan.

Yukiko Iioka1, Takako Iwata2, Hideko Yamauchi2.   

Abstract

BACKGROUND: The aim was to clarify subjective symptoms and quality of life (QOL) in breast cancer patients receiving hormone therapy.
METHODS: After obtaining approval from the research ethics committee, an observational study using a self-administered questionnaire was conducted at outpatient clinical oncology offices in 3 facilities that targeted breast cancer patients under the age of 50 who had been undergoing hormone therapy for less than 1 year. The study examined elements such as the breast cancer patients' basic information, symptoms, pain in daily life, QOL, and depression/anxiety.
RESULTS: There were 214 valid responses. The respondents had an average age of 43.6. Of them, 100% were also treated with Tamoxifen and 30% with LH-RH agonist. There were 75% who were cognizant of side effects. Difficult symptoms that occurred with high frequency were stiff shoulders/back pain, decreased physical strength, hot flashes, and sweating. Over half the respondents were uncertain as to whether the subjective symptoms were side effects. They lost confidence in their physical strength and felt distressed over weight gain. There were 51 with a HADS anxiety score of 8 or higher, and 46 who scored 8 points or higher for depression.
CONCLUSION: Breast cancer patients undergoing hormone therapy experience a variety of pains, and some also have serious psychological symptoms. Reassessing support systems to examine screening and self-care support is an issue going forward.

Entities:  

Keywords:  Breast cancer; Hormone therapy; QOL; Symptom

Mesh:

Substances:

Year:  2019        PMID: 31297685     DOI: 10.1007/s12282-019-00993-0

Source DB:  PubMed          Journal:  Breast Cancer        ISSN: 1340-6868            Impact factor:   4.239


  4 in total

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