Literature DB >> 31297593

Which symptoms and problems do advanced cancer patients admitted to specialized palliative care report in addition to those included in the EORTC QLQ-C15-PAL? A register-based national study.

Leslye Rojas-Concha1,2, Maiken Bang Hansen3,4, Morten Aagaard Petersen3, Mogens Groenvold3,4.   

Abstract

PURPOSE: Patients in palliative care are willing to answer short questionnaires, like the EORTC QLQ-C15-PAL; however, patients may suffer from other symptoms and problems (S/Ps) not covered by such questionnaires. Therefore, to identify which other S/Ps patients experience, in addition to those already included in the EORTC QLQ-C15-PAL, we developed a brief instrument to supplement this questionnaire named WISP (Write In three Symptoms/Problems), permitting patients to report 1-3 additional S/Ps and their severity. We aim to investigate the nature, prevalence, and severity of S/Ps reported on WISP.
METHODS: A register-based study with data obtained from the Danish Palliative Care Database. This study included adults with advanced cancer admitted to specialized palliative care in Denmark, who reported S/Ps on WISP. S/Ps were categorized qualitatively, and their prevalence and severity were calculated.
RESULTS: Of the 5447 patients who completed the EORTC QLQ-C15-PAL, 1788 (32.8%) reported at least one symptom/problem using WISP. In total, 2796 S/Ps were reported; 24.8% were already covered by EORTC QLQ-C15-PAL; 63.6% were new, 10.1% were diagnoses and 1.6% could not be coded. S/Ps already covered and new were grouped into 61 categories. The most prevalent S/Ps reported were (in decreasing order) pain, edema, dizziness, impaired physical or emotional function, cough, and sweats. Overall, 85% of the S/Ps were rated as moderate to severe.
CONCLUSIONS: The WISP instrument strongly improves the recognition of S/Ps by combining standardization with individualization. We recommend its use for comprehensive symptom assessment alongside the EORTC QLQ-C15-PAL, and potentially also alongside the EORTC QLQ-C30.

Entities:  

Keywords:  Advanced cancer; EORTC QLQ-C15-PAL; Palliative care; Prevalence; Symptom assessment

Mesh:

Year:  2019        PMID: 31297593     DOI: 10.1007/s00520-019-04976-x

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  33 in total

Review 1.  Symptom prevalence in patients with incurable cancer: a systematic review.

Authors:  Saskia C C M Teunissen; Wendy Wesker; Cas Kruitwagen; Hanneke C J M de Haes; Emile E Voest; Alexander de Graeff
Journal:  J Pain Symptom Manage       Date:  2007-05-23       Impact factor: 3.612

Review 2.  The Edmonton Symptom Assessment System: a 15-year retrospective review of validation studies (1991--2006).

Authors:  Cheryl Nekolaichuk; Sharon Watanabe; Crystal Beaumont
Journal:  Palliat Med       Date:  2008-03       Impact factor: 4.762

3.  The Assessment of Quality of life at the End of Life (AQEL) questionnaire: a brief but comprehensive instrument for use in patients with cancer in palliative care.

Authors:  Ingela Henoch; Bertil Axelsson; Bengt Bergman
Journal:  Qual Life Res       Date:  2010-03-13       Impact factor: 4.147

4.  Validity of the McGill Quality of Life Questionnaire in the palliative care setting: a multi-centre Canadian study demonstrating the importance of the existential domain.

Authors:  S R Cohen; B M Mount; E Bruera; M Provost; J Rowe; K Tong
Journal:  Palliat Med       Date:  1997-01       Impact factor: 4.762

5.  Self-assessment in cancer patients referred to palliative care: a study of feasibility and symptom epidemiology.

Authors:  Annette S Strömgren; Dorthe Goldschmidt; Mogens Groenvold; Morten Aa Petersen; Pernille T Jensen; Lise Pedersen; Linda Hoermann; Carsten Helleberg; Per Sjogren
Journal:  Cancer       Date:  2002-01-15       Impact factor: 6.860

6.  Symptom recognition in advanced cancer. A comparison of nursing records against patient self-rating.

Authors:  A S Strömgren; M Groenvold; A Sorensen; L Andersen
Journal:  Acta Anaesthesiol Scand       Date:  2001-10       Impact factor: 2.105

7.  The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients.

Authors:  E Bruera; N Kuehn; M J Miller; P Selmser; K Macmillan
Journal:  J Palliat Care       Date:  1991       Impact factor: 2.250

8.  Symptom evaluation in palliative medicine: patient report vs systematic assessment.

Authors:  Jade Homsi; Declan Walsh; Nilo Rivera; Lisa A Rybicki; Kristine A Nelson; Susan B Legrand; Mellar Davis; Michael Naughton; Dragoslav Gvozdjan; Hahn Pham
Journal:  Support Care Cancer       Date:  2006-01-10       Impact factor: 3.603

9.  The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology.

Authors:  N K Aaronson; S Ahmedzai; B Bergman; M Bullinger; A Cull; N J Duez; A Filiberti; H Flechtner; S B Fleishman; J C de Haes
Journal:  J Natl Cancer Inst       Date:  1993-03-03       Impact factor: 13.506

10.  "Now that you mention it, doctor ... ": symptom reporting and the need for systematic questioning in a specialist palliative care unit.

Authors:  Clare White; Damien McMullan; Julie Doyle
Journal:  J Palliat Med       Date:  2009-05       Impact factor: 2.947

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  3 in total

1.  Prevalence and associated factors of orphan symptoms in advanced cancer patients: a multicenter observational study.

Authors:  Kaoru Nishijima; Yoshiyuki Kizawa; Toshihiro Yamauchi; Takuya Odagiri; Tetsuya Ito; Keisuke Kaneishi; Keiji Shimizu; Tatsuya Morita; Masanori Mori
Journal:  Support Care Cancer       Date:  2021-03-16       Impact factor: 3.603

2.  Retrospective Observational Study on the Characteristics of Pain and Associated Factors of Breakthrough Pain in Advanced Cancer Patients.

Authors:  Rongrong Fan; Xuying Li; Siyu Yang; Xiaofan Bu; Yongyi Chen; Ying Wang; Cuiling Qiu
Journal:  Pain Res Manag       Date:  2022-04-14       Impact factor: 2.667

Review 3.  A Narrative Review on the Collection and Use of Electronic Patient-Reported Outcomes in Cancer Survivorship Care with Emphasis on Symptom Monitoring.

Authors:  Corina J G van den Hurk; Floortje Mols; Manuela Eicher; Raymond J Chan; Annemarie Becker; Gijs Geleijnse; Iris Walraven; Annemarie Coolbrandt; Maryam Lustberg; Galina Velikova; Andreas Charalambous; Bogda Koczwara; Doris Howell; Ethan M Basch; Lonneke V van de Poll-Franse
Journal:  Curr Oncol       Date:  2022-06-17       Impact factor: 3.109

  3 in total

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