| Literature DB >> 31296776 |
Matthew R Lozier1, Alexandra M Sanchez2, John J Lee3, Leonardo J Tamariz4, Gabriel A Valle4,5.
Abstract
Debates exist regarding the merit of starting one dialysis modality over the other for improved cardiovascular outcomes. Five previously published prospective and retrospective cohort studies have reported inconsistent conclusions on this topic. The aim of this systematic review and meta-analysis is to evaluate the influence initiation of hemodialysis (HD) vs peritoneal dialysis (PD) may have on the relative risk (RR) of subsequent development of adverse cardiovascular events (ACVE) in patients with end-stage renal disease (ESRD). Of the 518 records identified, 5 cohort studies, assessing a total of 47,062 patients were included in the meta-analysis. With regard to the subsequent development of ACVE following initiation on the different dialysis modalities, the pooled RR was found to be non-significant. Peritoneal dialysis is a suitable and cost-effective alternative to HD for ESRD patients at risk of cardiovascular disease.Entities:
Keywords: Renal replacement therapy; adverse cardiovascular events; hyper-dynamic flow; metabolic syndrome; pharmaco-therapeutic; residual renal function
Mesh：
Year: 2019 PMID： 31296776 DOI： 10.3747/pdi.2018.00227
Source DB: PubMed Journal: Perit Dial Int ISSN： 0896-8608 Impact factor: 1.756