Literature DB >> 31296771

Posterior parietal cortex plays a causal role in perceptual and categorical decisions.

Yang Zhou1, David J Freedman1.   

Abstract

Posterior parietal cortex (PPC) activity correlates with monkeys' decisions during visual discrimination and categorization tasks. However, recent work has questioned whether decision-correlated PPC activity plays a causal role in such decisions. That study focused on PPC's contribution to motor aspects of decisions (deciding where to move), but not sensory evaluation aspects (deciding what you are looking at). We employed reversible inactivation to compare PPC's contributions to motor and sensory aspects of decisions. Inactivation affected both aspects of behavior, but preferentially impaired decisions when visual stimuli, rather than motor response targets, were in the inactivated visual field. This demonstrates a causal role for PPC in decision-making, with preferential involvement in evaluating attended task-relevant sensory stimuli compared with motor planning.
Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Year:  2019        PMID: 31296771      PMCID: PMC7346736          DOI: 10.1126/science.aaw8347

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  43 in total

1.  Microsaccadic eye movements and firing of single cells in the striate cortex of macaque monkeys.

Authors:  S Martinez-Conde; S L Macknik; D H Hubel
Journal:  Nat Neurosci       Date:  2000-03       Impact factor: 24.884

2.  Parietal activity and the perceived direction of ambiguous apparent motion.

Authors:  Ziv M Williams; John C Elfar; Emad N Eskandar; Louis J Toth; John A Assad
Journal:  Nat Neurosci       Date:  2003-06       Impact factor: 24.884

3.  Experience-dependent representation of visual categories in parietal cortex.

Authors:  David J Freedman; John A Assad
Journal:  Nature       Date:  2006-08-27       Impact factor: 49.962

4.  Posterior Parietal Cortex Guides Visual Decisions in Rats.

Authors:  Angela M Licata; Matthew T Kaufman; David Raposo; Michael B Ryan; John P Sheppard; Anne K Churchland
Journal:  J Neurosci       Date:  2017-04-13       Impact factor: 6.167

Review 5.  Attention, intention, and priority in the parietal lobe.

Authors:  James W Bisley; Michael E Goldberg
Journal:  Annu Rev Neurosci       Date:  2010       Impact factor: 12.449

6.  Dynamics of neuronal responses in macaque MT and VIP during motion detection.

Authors:  Erik P Cook; John H R Maunsell
Journal:  Nat Neurosci       Date:  2002-10       Impact factor: 24.884

7.  Biased associative representations in parietal cortex.

Authors:  Jamie K Fitzgerald; David J Freedman; Alessandra Fanini; Sharath Bennur; Joshua I Gold; John A Assad
Journal:  Neuron       Date:  2013-01-09       Impact factor: 17.173

8.  Preferential encoding of visual categories in parietal cortex compared with prefrontal cortex.

Authors:  Sruthi K Swaminathan; David J Freedman
Journal:  Nat Neurosci       Date:  2012-01-15       Impact factor: 24.884

9.  Sequential sensory and decision processing in posterior parietal cortex.

Authors:  Guilhem Ibos; David J Freedman
Journal:  Elife       Date:  2017-04-24       Impact factor: 8.140

10.  Microstimulation of macaque area LIP affects decision-making in a motion discrimination task.

Authors:  Timothy D Hanks; Jochen Ditterich; Michael N Shadlen
Journal:  Nat Neurosci       Date:  2006-04-09       Impact factor: 24.884

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  20 in total

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Authors:  Seong-Hah Cho; Trinity Crapse; Piercesare Grimaldi; Hakwan Lau; Michele A Basso
Journal:  J Neurosci       Date:  2021-02-23       Impact factor: 6.167

2.  Superior colliculus activates new perspectives on decision-making.

Authors:  Kenneth W Latimer; Alexander C Huk
Journal:  Nat Neurosci       Date:  2021-08       Impact factor: 24.884

3.  Cocaine-related alterations in fronto-parietal gray matter volume correlate with trait and behavioral impulsivity.

Authors:  Christina S Meade; Ryan P Bell; Sheri L Towe; Shana A Hall
Journal:  Drug Alcohol Depend       Date:  2019-11-20       Impact factor: 4.492

4.  Parietal Cortex Is Required for the Integration of Acoustic Evidence.

Authors:  Justin D Yao; Justin Gimoto; Christine M Constantinople; Dan H Sanes
Journal:  Curr Biol       Date:  2020-07-02       Impact factor: 10.834

5.  Attention network modulation via tRNS correlates with attention gain.

Authors:  Federica Contò; Grace Edwards; Sarah Tyler; Danielle Parrott; Emily Grossman; Lorella Battelli
Journal:  Elife       Date:  2021-11-26       Impact factor: 8.140

6.  Cognitive experience alters cortical involvement in goal-directed navigation.

Authors:  Charlotte Arlt; Roberto Barroso-Luque; Shinichiro Kira; Carissa A Bruno; Ningjing Xia; Selmaan N Chettih; Sofia Soares; Noah L Pettit; Christopher D Harvey
Journal:  Elife       Date:  2022-06-23       Impact factor: 8.713

7.  Relationship Between the Activities of Gloss-Selective Neurons in the Macaque Inferior Temporal Cortex and the Gloss Discrimination Behavior of the Monkey.

Authors:  Mika Baba; Akiko Nishio; Hidehiko Komatsu
Journal:  Cereb Cortex Commun       Date:  2021-02-10

8.  Parietal Cortex Regulates Visual Salience and Salience-Driven Behavior.

Authors:  Xiaomo Chen; Marc Zirnsak; Gabriel M Vega; Eshan Govil; Stephen G Lomber; Tirin Moore
Journal:  Neuron       Date:  2020-02-10       Impact factor: 17.173

Review 9.  Unraveling circuits of visual perception and cognition through the superior colliculus.

Authors:  Michele A Basso; Martha E Bickford; Jianhua Cang
Journal:  Neuron       Date:  2021-02-05       Impact factor: 17.173

10.  Representational geometry of perceptual decisions in the monkey parietal cortex.

Authors:  Gouki Okazawa; Christina E Hatch; Allan Mancoo; Christian K Machens; Roozbeh Kiani
Journal:  Cell       Date:  2021-06-24       Impact factor: 66.850

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