Literature DB >> 31295514

Contacting of authors modified crucial outcomes of systematic reviews but was poorly reported, not systematic, and produced conflicting results.

Reint Meursinge Reynders1, Luisa Ladu2, Nicola Di Girolamo3.   

Abstract

OBJECTIVES: The objective of the study was to assess the prevalence, the reporting quality, the need, and the consequences of contacting of authors by Cochrane reviewers to obtain additional information for their reviews. STUDY DESIGN AND
SETTING: Cross-sectional study and survey on all new Cochrane intervention reviews published between January 1, 2016 and January 31, 2017.
RESULTS: The cross-sectional study found that reviewers had contacted or had tried to contact studies to obtain additional information in 73.4% (234/319) of reviews but reported poorly on the methods, outcomes, and consequences of this procedure. Most eligible studies in the reviews were poorly reported, but few reviewers 21.2% (65/306) reported that they had contacted these studies. The survey showed that risk of bias scores, Grading of Recommendations, Assessment, Development and Evaluation scores, the summary primary or secondary outcomes, and the summary effect size of the primary outcome of the review were changed as a consequence of contacting of authors. Thirty-five of one hundred and thirty (26.9%) reviews scored opposite outcomes for the same question in the cross-sectional study compared with the survey.
CONCLUSIONS: Our findings on contacting of authors by Cochrane reviewers showed relevant shortcomings in the current standards and transparency of Cochrane reviews. These shortcomings can compromise the validity and reproducibility of these reviews and affect a wide audience.
Copyright © 2019 Elsevier Inc. All rights reserved.

Keywords:  Author contact; Bias; Cochrane; Missing data; Poor reporting; Systematic review

Mesh:

Year:  2019        PMID: 31295514     DOI: 10.1016/j.jclinepi.2019.07.001

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


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