| Literature DB >> 31293363 |
Yecai Huang1, Mei Feng1, Jun Yin1, Bingyu Fu1, Jinyi Lang1.
Abstract
Sacrococcygeal teratoma is the most common germ cell neoplasia that consists of tissues derived from primitive germ layers. Approximately 10-20% of patients are malignant. Because of the high rate of recurrence, treatment strategies for malignant sacrococcygeal teratomas are limited. Hence, we report a case of malignant sacrococcygeal teratoma treated with concurrent chemoradiotherapy plus adjuvant chemotherapy and review the literature. This case report indicates that chemoradiation plus adjuvant chemotherapy may be a treatment option for malignant SCT which is not technically resectable or with residual lesion after surgery.Entities:
Keywords: AFP, α-fetoprotein; Chemotherapy; MRI, magnetic resonance imaging; Malignant sacrococcygeal teratoma; PEB, etoposide (VP-16), cisplatin (DDP) and bleomycin (BLM); Radiotherapy; SCT, sacrococcygeal teratoma; VMAT, volume-modulated arc therapy; hCG, human chorionic gonadotropin
Year: 2019 PMID： 31293363 PMCID： PMC6595120 DOI： 10.1016/j.rpor.2019.06.002
Source DB: PubMed Journal: Rep Pract Oncol Radiother ISSN： 1507-1367