Tamara Ownsworth1, Suzanne Chambers2,3,4,5,6, Joanne F Aitken3,6,7,8,9, Matthew Foote10,11, Mark B Pinkham10,11, Louisa G Gordon8,12,13, Gemma Lock7, Brigid Hanley7, Tracey Gardner7, Stephanie Jones1, Julia Robertson1, David Shum1,14, Elizabeth Conlon1. 1. School of Applied Psychology, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia. 2. University of Technology Sydney, Sydney, New South Wales, Australia. 3. Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia. 4. Australian and New Zealand Urogenital and Prostate Cancer (ANZUP) Trials Group, Sydney, New South Wales, Australia. 5. Exercise Medicine Research Institute, Edith Cowan University, Perth, Western Australia, Australia. 6. Institute for Resilient Regions, University of Southern Queensland, Toowoomba, Queensland, Australia. 7. Cancer Council Queensland, Brisbane, Queensland, Australia. 8. School of Public Health, University of Queensland, Brisbane, Queensland, Australia. 9. School of Research-Public Health, Queensland University of Technology, Brisbane, Queensland, Australia. 10. Department of Radiation Oncology, Princess Alexandra Hospital, Brisbane, Queensland, Australia. 11. School of Medicine, University of Queensland, Brisbane, Queensland, Australia. 12. QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. 13. School of Nursing, Queensland University of Technology, Brisbane, Queensland, Australia. 14. Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hong Kong, China.
Abstract
OBJECTIVE: There is a lack of research on interventions that address the specific psychosocial needs of people with brain tumour and their families. This paper describes the protocol for a pragmatic randomised control trial (RCT) evaluating the clinical efficacy and cost-effectiveness of the Making Sense of Brain Tumour program delivered via telehealth (Tele-MAST) relative to standard care. METHODS: The 148 adults with primary brain tumour will be randomly allocated to the 10-session Tele-MAST videoconferencing program or standard care from a cancer counselling service. The primary outcome is level of depression and secondary outcomes are quality of life, mental health and incremental cost per quality-adjusted life year. The mental health and quality of life of family members will also be assessed. Assessments will be conducted at pre-intervention, post-intervention (primary endpoint), 6-weeks post-intervention and 6-months post-intervention. The main analysis will determine whether the Tele-MAST intervention is more effective than standard care at post-intervention, and whether these effects are sustained at follow-up. CONCLUSION: Results will indicate whether the Tele-MAST program is associated with better clinical outcomes and is more cost-effective than existing cancer support services. Such outcomes will contribute to effective and accessible psychosocial care for the brain tumour population.
RCT Entities:
OBJECTIVE: There is a lack of research on interventions that address the specific psychosocial needs of people with brain tumour and their families. This paper describes the protocol for a pragmatic randomised control trial (RCT) evaluating the clinical efficacy and cost-effectiveness of the Making Sense of Brain Tumour program delivered via telehealth (Tele-MAST) relative to standard care. METHODS: The 148 adults with primary brain tumour will be randomly allocated to the 10-session Tele-MAST videoconferencing program or standard care from a cancer counselling service. The primary outcome is level of depression and secondary outcomes are quality of life, mental health and incremental cost per quality-adjusted life year. The mental health and quality of life of family members will also be assessed. Assessments will be conducted at pre-intervention, post-intervention (primary endpoint), 6-weeks post-intervention and 6-months post-intervention. The main analysis will determine whether the Tele-MAST intervention is more effective than standard care at post-intervention, and whether these effects are sustained at follow-up. CONCLUSION: Results will indicate whether the Tele-MAST program is associated with better clinical outcomes and is more cost-effective than existing cancer support services. Such outcomes will contribute to effective and accessible psychosocial care for the brain tumour population.
Authors: Lekhaj C Daggubati; Daniel G Eichberg; Michael E Ivan; Simon Hanft; Alireza Mansouri; Ricardo J Komotar; Randy S D'Amico; Brad E Zacharia Journal: World Neurosurg Date: 2020-05-22 Impact factor: 2.104
Authors: Quirien Oort; Hanneke Zwinkels; Johan A F Koekkoek; Maaike J Vos; Jaap C Reijneveld; Martin J B Taphoorn; Linda Dirven Journal: Psychooncology Date: 2022-01-28 Impact factor: 3.955