Literature DB >> 31290640

An Analysis of Cost-Effectiveness of Stents Used in the Treatment of Coronary Artery Disease

Ferda Işıkçelik1, İsmail Ağırbaş1, Cansın Tulunay Kaya2.   

Abstract

Background: There is only limited information about the cost-effectiveness of drug-eluting stents compared with bare-metal stents in Turkey. Aims: To evaluate bare-metal and drug-eluting stents used in the treatment of coronary artery disease from the perspective of the reimbursement institution with cost-effectiveness analysis. Study Design: Retrospective cost-effectiveness analysis.
Methods: In our study, 329 patients diagnosed with coronary artery disease and treated with bare-metal or drug-eluting stents in the cardiology clinics of a public university hospital between January 1 and December 31, 2016 were investigated. Bare-metal and drug-eluting stents used in the treatment of coronary artery disease were evaluated retrospectively with cost-effectiveness analysis from the perspective of the reimbursement institution.
Results: The cost of treatment with a bare-metal stent was 2,131.41 Turkish Liras, and the cost of treatment with a drug-eluting stent was 3,546.14 Turkish Liras; the Quality Adjusted Life Years value of treatment with a bare-metal stent was 0.8371, and the Quality Adjusted Life Years value of treatment with a drug-eluting stent was 0.8924. All these data were analyzed by decision tree. As a result of decision tree analysis, the weighted cost of treatment with a bare-metal stent was 2,340.71 Turkish Liras and weighted Quality Adjusted Life Years value was 0.8332; and the weighted cost of treatment with drug-eluting stent was 3,970.90 Turkish Liras and the weighted Quality Adjusted Life Years value of the treatment with drug-eluting stent was 0.8911. With these values, the additional cost-effectiveness ratio was calculated as 28,179.12 Turkish Liras per acquired Quality Adjusted Life Years. The additional cost-effectiveness ratio is in the first zone in the cost-effectiveness plane and below the very threshold of cost-effectiveness.
Conclusion: In our study, it was concluded that drug-eluting stents are cost effective compared with bare-metal stents in the treatment of coronary artery disease. Considering the cost and effectiveness of the drug-eluting stent, it is thought that increasing reimbursement for this technology by the reimbursement agency would be beneficial for the service provider.

Entities:  

Keywords:  Coronary artery disease; cost-effectiveness analysis; economic evaluation; health technology assessment; stents

Year:  2019        PMID: 31290640      PMCID: PMC6711256          DOI: 10.4274/balkanmedj.galenos.2019.2018.12.28

Source DB:  PubMed          Journal:  Balkan Med J        ISSN: 2146-3123            Impact factor:   2.021


  18 in total

1.  Cost-effectiveness of drug-eluting coronary stents in Quebec, Canada.

Authors:  James M Brophy; Lonny J Erickson
Journal:  Int J Technol Assess Health Care       Date:  2005       Impact factor: 2.188

Review 2.  [Drug-eluting stents in multivessel coronary artery disease: Was one of the important fortresses of surgery conquered?].

Authors:  Arda Sanli Okmen; Ertan Okmen
Journal:  Anadolu Kardiyol Derg       Date:  2009-08

3.  [Turkish Adult Risk Factor survey 2014: Overall mortality and coronary disease incidence in Turkey's geographic regions].

Authors:  Altan Onat; Süleyman Karakoyun; Tuğba Akbaş; Fatma Özpamuk Karadeniz; Yusuf Karadeniz; Hakan Çakır; Barış Şimşek; Günay Can
Journal:  Turk Kardiyol Dern Ars       Date:  2015-06

4.  Do pre-procedural laboratory parameters predict drug-eluting stent restenosis?

Authors:  Aslı Tanındı; Berkay Ekici; Hasan Fehmi Töre
Journal:  Turk Kardiyol Dern Ars       Date:  2015-07

5.  Nebivolol prevents remodeling in a rat myocardial infarction model: an echocardiographic study.

Authors:  Güldem Olguner Mercanoğlu; Burak Pamukçu; Nurhas Safran; Fehmi Mercanoğlu; Francesco Fici; Mehmet Güngör
Journal:  Anadolu Kardiyol Derg       Date:  2010-02

6.  Analysis of the cost-effectiveness of drug-eluting and bare-metal stents in coronary disease.

Authors:  Esmeralci Ferreira; Denizar Vianna Araújo; Vitor Manuel Pereira Azevedo; Cyro Vargues Rodrigues; Alcides Ferreira; Camillo de Lellis Junqueira; José Geraldo de Castro Amino; Mara Lucia Farias; Antonio Farias Neto; Denilson Campos de Albuquerque
Journal:  Arq Bras Cardiol       Date:  2010-03       Impact factor: 2.000

7.  Economic evaluation of sirolimus-eluting stents.

Authors:  Fiona M Shrive; Braden J Manns; P Diane Galbraith; Merril L Knudtson; William A Ghali
Journal:  CMAJ       Date:  2005-02-01       Impact factor: 8.262

8.  Cost-effectiveness of drug-eluting stents in a US Medicare setting:a cost-utility analysis with 3-year clinical follow-up data.

Authors:  Matthias Bischof; Matthias Briel; Heiner C Bucher; Alain Nordmann
Journal:  Value Health       Date:  2009 Jul-Aug       Impact factor: 5.725

9.  Thresholds for the cost-effectiveness of interventions: alternative approaches.

Authors:  Elliot Marseille; Bruce Larson; Dhruv S Kazi; James G Kahn; Sydney Rosen
Journal:  Bull World Health Organ       Date:  2014-12-15       Impact factor: 9.408

10.  Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Authors: 
Journal:  Lancet       Date:  2017-09-16       Impact factor: 79.321

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  2 in total

1.  Drug-eluting Vein Graft with Acetylsalicylic Acid-Ticagrelor-Unfractionated Heparin Complex Inhibits Early Graft Thrombosis

Authors:  Ercan Akşit; Tolga Kurt; Başak Büyük; Ömer Çokkalender
Journal:  Balkan Med J       Date:  2020-05-01       Impact factor: 2.021

2.  A Liver Transplant Patient on Everolimus Treatment Presented with Acute Anterior Myocardial Infarction: Does the Type of Drug-eluting Stent Matter?

Authors:  Muhammet Gürdoğan; Kenan Yalta; Mustafa Adem Yılmaztepe; Servet Altay; Ömer Ferudun Akkuş
Journal:  Balkan Med J       Date:  2019-12-27       Impact factor: 2.021

  2 in total

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