Literature DB >> 31290510

A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles.

Arnab Banerjee1, Vitor Alves2, Tiago Rondão3, José Sereno2, Ângela Neves2, Miguel Lino4, Andreia Ribeiro1, Antero J Abrunhosa2, Lino S Ferreira4.   

Abstract

Here we report a two-step surface modification methodology to radiolabel small extracellular vesicles (SEVs) with 64CuCl2 for PET/MRI imaging. The modification did not change or damage the morphology, surface receptor proteins and internal RNA content. Radiolabeled SEVs could be detected in organs with low accumulation such as the brain (0.4-0.5% ID g-1) and their brain location determined by MRI.

Entities:  

Year:  2019        PMID： 31290510     DOI： 10.1039/c9nr02512j

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


  10 in total

Review 1.  Non-Invasive imaging of extracellular vesicles: Quo vaditis in vivo?

Authors:  Dian R Arifin; Kenneth W Witwer; Jeff W M Bulte
Journal:  J Extracell Vesicles       Date:  2022-07

Review 2.  Harnessing the Therapeutic Potential of Extracellular Vesicles for Biomedical Applications Using Multifunctional Magnetic Nanomaterials.

Authors:  Letao Yang; Kapil D Patel; Christopher Rathnam; Ramar Thangam; Yannan Hou; Heemin Kang; Ki-Bum Lee
Journal:  Small       Date:  2022-02-08       Impact factor: 15.153

Review 3.  Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research.

Authors:  Giorgia Ailuno; Sara Baldassari; Francesco Lai; Tullio Florio; Gabriele Caviglioli
Journal:  Cells       Date:  2020-12-01       Impact factor: 6.600

Review 4.  In Vivo Tracking of Extracellular Vesicles by Nuclear Imaging: Advances in Radiolabeling Strategies.

Authors:  Sara Almeida; Liliana Santos; Amílcar Falcão; Célia Gomes; Antero Abrunhosa
Journal:  Int J Mol Sci       Date:  2020-12-11       Impact factor: 5.923

Review 5.  Radiolabelling of Extracellular Vesicles for PET and SPECT imaging.

Authors:  Azalea A Khan; Rafael T M de Rosales
Journal:  Nanotheranostics       Date:  2021-02-13

6.  Exogenous loading of miRNAs into small extracellular vesicles.

Authors:  Ricardo C de Abreu; Cristiana V Ramos; Clarissa Becher; Miguel Lino; Carlos Jesus; Paula A da Costa Martins; Patrícia A T Martins; Maria João Moreno; Hugo Fernandes; Lino Ferreira
Journal:  J Extracell Vesicles       Date:  2021-08-02

7.  PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling.

Authors:  Azalea A Khan; Francis Man; Farid N Faruqu; Jana Kim; Fahad Al-Salemee; Amaia Carrascal-Miniño; Alessia Volpe; Revadee Liam-Or; Paul Simpson; Gilbert O Fruhwirth; Khuloud T Al-Jamal; Rafael T M de Rosales
Journal:  Bioconjug Chem       Date:  2022-02-28       Impact factor: 4.774

8.  Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides.

Authors:  Zhanchi Zhu; Yuanxin Zhai; Ying Hao; Quanwei Wang; Fang Han; Wenlong Zheng; Jing Hong; Leisha Cui; Wei Jin; Sancheng Ma; Lingyan Yang; Guosheng Cheng
Journal:  J Extracell Vesicles       Date:  2022-08

Review 9.  Native and bioengineered extracellular vesicles for cardiovascular therapeutics.

Authors:  Ricardo Cerqueira de Abreu; Hugo Fernandes; Paula A da Costa Martins; Susmita Sahoo; Costanza Emanueli; Lino Ferreira
Journal:  Nat Rev Cardiol       Date:  2020-06-01       Impact factor: 32.419

Review 10.  Chemically Modified Extracellular Vesicles and Applications in Radiolabeling and Drug Delivery.

Authors:  Elisa-Racky N'Diaye; Nicola Salvatore Orefice; Catherine Ghezzi; Ahcène Boumendjel
Journal:  Pharmaceutics       Date:  2022-03-16       Impact factor: 6.321
  10 in total

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