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Literature DB >> 3128977

Induction of indoleamine dioxygenase by interferon in mice: a study with different recombinant interferons and various cytokines.

Abstract

Since it is important the availability of a specific marker for interferon induction in vivo, we investigated the effect of different recombinant interferons and various cytokines on indoleamine 2,3-dioxygenase activity. Although with different magnitude, recombinant interferon-alpha A/D (Bgl II) hybrid, interferon-gamma and tumor necrosis factor, all increase the activity of this enzyme, whereas interleukin-1, recombinant interferon-alpha A and interferon-alpha D do not induce this activity in mice lung tissue. Dexamethasone is able to inhibit indoleamine 2,3-dioxygenase induction by lipopolysaccharide or by interferon-alpha A/D but it fails to prevent the induction by interferon-gamma.

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Year: 1988 PMID： 3128977 DOI： 10.1016/s0006-291x(88)80705-8

Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575

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Cited

14 in total

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3. Interferon gamma-resistant mutants are defective in the induction of indoleamine 2,3-dioxygenase.

Authors: G S Feng; M W Taylor
Journal: Proc Natl Acad Sci U S A Date: 1989-09 Impact factor: 11.205

4. 3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival.

Authors: Sarah S Zaher; Conrad Germain; Hongmei Fu; Daniel F P Larkin; Andrew J T George
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5. Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron(III).

Authors: S J Gebran; Y Yamamoto; C Newton; T W Klein; H Friedman
Journal: Infect Immun Date: 1994-08 Impact factor: 3.441

6. Immunocytochemical localization of the endogenous neuroexcitotoxin quinolinate in human peripheral blood monocytes/macrophages and the effect of human T-cell lymphotropic virus type I infection.

Authors: C N Venkateshan; R Narayanan; M G Espey; J R Moffett; D C Gajdusek; C J Gibbs; M A Namboodiri
Journal: Proc Natl Acad Sci U S A Date: 1996-02-20 Impact factor: 11.205

10. Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites.

Authors: Peter Terness; Thomas M Bauer; Lars Röse; Christoph Dufter; Andrea Watzlik; Helmut Simon; Gerhard Opelz
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