| Literature DB >> 31288712 |
Li Xu1,2, Long-Fei Wu1,2, Fei-Yan Deng1,2.
Abstract
Exosomes are 30-120nm long endocytic membrane-derived vesicles, which are secreted by various types of cells and stably present in body fluids, such as plasma, urine, saliva and breast milk. Exosomes participate in intercellular communication. Recently accumulative studies have suggested that exosomes may serve as novel biomarkers for disease diagnosis and prognosis. Herein, we reviewed the biological features of exosomes, technologies for exosome isolation and identification, as well as progress in exosomal biomarker identification, highlighting the relevance of exosome to human diseases and significance and great potential in translational medicine. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Biomarker; Diagnosis; Exosome; Isolation; Protein; RNA.
Year: 2019 PMID： 31288712 DOI： 10.2174/1566524019666190429144310
Source DB: PubMed Journal: Curr Mol Med ISSN： 1566-5240 Impact factor: 2.222