Literature DB >> 31287988

The Stromal and Immune Landscape of Colorectal Cancer Progression during Anti-EGFR Therapy.

Irene Catalano1, Livio Trusolino2.   

Abstract

In this issue of Cancer Cell, Woolston et al. show that colorectal cancers that become refractory to initially effective anti-EGFR therapy contain an abundance of stromal and immune cells, irrespective of the contextual presence of resistance-conferring mutations. This reconfiguration puts forward therapeutic opportunities for patients who relapse on EGFR-targeting treatment.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31287988     DOI: 10.1016/j.ccell.2019.06.001

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  5 in total

1.  An approach using Caenorhabditis elegans screening novel targets to suppress tumour cell proliferation.

Authors:  Yu-Qin Mao; San-Feng Han; Shi-Long Zhang; Zheng-Yan Zhang; Chao-Yue Kong; Hui-Ling Chen; Zhan-Ming Li; Pei-Ran Cai; Bing Han; Li-Shun Wang
Journal:  Cell Prolif       Date:  2020-05-25       Impact factor: 6.831

2.  Identification of immune landscape signatures associated with clinical and prognostic features of hepatocellular carcinoma.

Authors:  Hongmei Yan; Yuchuan Chen; Kai Wang; Lu Yu; Xixin Huang; Qianyu Li; Yuwen Xie; Jiayu Lin; Yueyun He; Xinyu Yi; Yanzhi Wang; Longhua Chen; Yi Ding; Yiyi Li
Journal:  Aging (Albany NY)       Date:  2020-10-13       Impact factor: 5.682

3.  Analysis of Tumor Microenvironment Characteristics in Bladder Cancer: Implications for Immune Checkpoint Inhibitor Therapy.

Authors:  Xingyu Chen; Haotian Chen; Dong He; Yaxin Cheng; Yuxing Zhu; Mengqing Xiao; Hua Lan; Zhanwang Wang; Ke Cao
Journal:  Front Immunol       Date:  2021-04-15       Impact factor: 7.561

4.  Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer.

Authors:  Antonio Tapia-Galisteo; Íñigo Sánchez Rodríguez; Oscar Aguilar-Sopeña; Seandean Lykke Harwood; Javier Narbona; Mariola Ferreras Gutierrez; Rocío Navarro; Laura Martín-García; Cesáreo Corbacho; Marta Compte; Javier Lacadena; Francisco J Blanco; Patrick Chames; Pedro Roda-Navarro; Luis Álvarez-Vallina; Laura Sanz
Journal:  Oncoimmunology       Date:  2022-02-07       Impact factor: 8.110

5.  NOP14 regulates the growth, migration, and invasion of colorectal cancer cells by modulating the NRIP1/GSK-3β/β-catenin signaling pathway.

Authors:  Xuanjin Zhu; Weilu Jia; Yong Yan; Yong Huang; Bailin Wang
Journal:  Eur J Histochem       Date:  2021-07-02       Impact factor: 3.188

  5 in total

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