Literature DB >> 31286154

CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor. Reply to Pagni PP, Wolf A, Lo Conte M et al [letter].

Gisela M Vaitaitis1,2, Michael H Olmstead3,4, Dan M Waid1,2, Jessica R Carter1,2,5, David H Wagner6,7.   

Abstract

Entities:  

Keywords:  Autoimmunity; CD154; CD40; Therapeutic; Type 1 diabetes

Mesh：

Substances：

Year:  2019        PMID： 31286154      PMCID： PMC6679809          DOI： 10.1007/s00125-019-4945-7

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  8 in total

1.  CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity.

Authors:  Gisela M Vaitaitis; David H Wagner
Journal:  Mol Immunol       Date:  2010-06-19       Impact factor: 4.407

2.  Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation.

Authors:  Hyun-Jung An; Young Jin Kim; Dong Hyun Song; Beom Suk Park; Ho Min Kim; Ju Dong Lee; Sang-Gi Paik; Jie-Oh Lee; Hayyoung Lee
Journal:  J Biol Chem       Date:  2011-02-01       Impact factor: 5.157

3.  CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor.

Authors:  Philippe P Pagni; Anitra Wolf; Mauro Lo Conte; Ronald Yeh; Guangsen Fu; Fa Liu; Matthias von Herrath; Ken Coppieters
Journal:  Diabetologia       Date:  2019-05-17       Impact factor: 10.122

4.  A CD40 targeting peptide prevents severe symptoms in experimental autoimmune encephalomyelitis.

Authors:  Gisela M Vaitaitis; Martin G Yussman; David H Wagner
Journal:  J Neuroimmunol       Date:  2019-03-21       Impact factor: 3.478

5.  Regulation of CD40 function by its isoforms generated through alternative splicing.

Authors:  M Tone; Y Tone; P J Fairchild; M Wykes; H Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

6.  A CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice.

Authors:  Gisela M Vaitaitis; Michael H Olmstead; Dan M Waid; Jessica R Carter; David H Wagner
Journal:  Diabetologia       Date:  2014-08-08       Impact factor: 10.122

7.  CD40 interacts directly with RAG1 and RAG2 in autoaggressive T cells and Fas prevents CD40-induced RAG expression.

Authors:  Gisela M Vaitaitis; David H Wagner
Journal:  Cell Mol Immunol       Date:  2013-09-16       Impact factor: 11.530

8.  Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity.

Authors:  Gisela M Vaitaitis; David H Wagner
Journal:  PLoS One       Date:  2012-06-07       Impact factor: 3.240
  8 in total
  1 in total

1.  CD40-targeting KGYY15 peptides do not efficiently block the CD40-CD40L interaction.

Authors:  Damir Bojadzic; Peter Buchwald
Journal:  Diabetologia       Date:  2019-09-09       Impact factor: 10.122
  1 in total

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