Literature DB >> 3128502

Gallium citrate, a new sensitizer of cells to hyperthermia.

K Shinohara1, N Kawakami, M Kugotani, H Nakano.   

Abstract

The killing effects of heat were studied on cultured mammalian cells (L5178Y) pre-incubated with gallium (Ga) citrate, which is a popular tumor-imaging diagnostic agent. The cells showed higher sensitivity to heat when they were pre-incubated with Ga-citrate. The pre-incubated cells showed decreased ATP levels, and this may be responsible for the heat-sensitizing effect.

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Year:  1988        PMID： 3128502      PMCID： PMC5907758          DOI： 10.1111/j.1349-7006.1988.tb00006.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN： 0910-5050


  20 in total

1.  Radiosensitivities of murine lymphoma L5178Y cells in a multi-cellular colony system.

Authors:  K Shinoara; S Okada
Journal:  J Radiat Res       Date:  1972-06       Impact factor: 2.724

2.  Sensitization of cultured Chinese hamster cells to 42 degrees C hyperthermia by pentalenolactone, an inhibitor of glycolytic ATP synthesis.

Authors:  W A Nagle; A J Moss; K J Henle
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1985-11

Review 3.  Hyperthermia in cancer therapy: the biological basis and unresolved questions.

Authors:  L E Gerweck
Journal:  Cancer Res       Date:  1985-08       Impact factor: 12.701

4.  Role of lysosomes in gallium concentration by mammalian tissues.

Authors:  J P Berry; M F Poupon; S Galle; F Escaig
Journal:  Biol Cell       Date:  1984       Impact factor: 4.458

5.  Evaluation of gallium nitrate in metastatic or locally recurrent squamous cell carcinoma of the head and neck: a Southwest Oncology Group study.

Authors:  D A Decker; J J Costanzi; J D McCracken; L H Baker
Journal:  Cancer Treat Rep       Date:  1984 Jul-Aug

6.  Early change of adenosine triphosphate levels in L5178Y cells during hyperthermia.

Authors:  K Shinohara; M Kugotani; J Ishiwata; T Matsuda
Journal:  Jpn J Cancer Res       Date:  1987-04

7.  Phase II evaluation of bolus gallium nitrate in lymphoproliferative disorders: a Southeastern Cancer Study Group trial.

Authors:  J Keller; A Bartolucci; J T Carpenter; J Feagler
Journal:  Cancer Treat Rep       Date:  1986-10

8.  Enhancement of hyperthermia-induced cytotoxicity upon ATP deprivation.

Authors:  F Laval; S Michel
Journal:  Cancer Lett       Date:  1982-01       Impact factor: 8.679

9.  Phase II trial of gallium nitrate in patients with advanced malignant melanoma.

Authors:  E S Casper; G F Stanton; P P Sordillo; R Parente; R A Michaelson; V Vinceguerra
Journal:  Cancer Treat Rep       Date:  1985-09

Review 10.  Mechanism of gallium-67 accumulation in inflammatory lesions.

Authors:  M F Tsan
Journal:  J Nucl Med       Date:  1985-01       Impact factor: 10.057
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