Literature DB >> 31284790

Transforming cancer drug discovery with Big Data and AI.

Paul Workman1, Albert A Antolin1,2, Bissan Al-Lazikani1,2.   

Abstract

Entities:  

Keywords:  Big Data; Big Knowledge; artificial intelligence; cancer; data analytics; data integration; drug discovery; machine learning; multidisciplinary data

Mesh：

Substances：

Year:  2019        PMID： 31284790     DOI： 10.1080/17460441.2019.1637414

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN： 1746-0441            Impact factor:   6.098


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  7 in total

1.  Artificial intelligence in clinical research of cancers.

Authors:  Dan Shao; Yinfei Dai; Nianfeng Li; Xuqing Cao; Wei Zhao; Li Cheng; Zhuqing Rong; Lan Huang; Yan Wang; Jing Zhao
Journal:  Brief Bioinform       Date:  2022-01-17       Impact factor: 11.622

2.  Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1-Mutant Diffuse Intrinsic Pontine Glioma.

Authors:  Diana M Carvalho; Peter J Richardson; Nagore Olaciregui; Reda Stankunaite; Cinzia Lavarino; Valeria Molinari; Elizabeth A Corley; Daniel P Smith; Ruth Ruddle; Adam Donovan; Akos Pal; Florence I Raynaud; Sara Temelso; Alan Mackay; John P Overington; Anne Phelan; David Sheppard; Andrew Mackinnon; Bassel Zebian; Safa Al-Sarraj; Ashirwad Merve; Jeremy Pryce; Jacques Grill; Michael Hubank; Ofelia Cruz; Andres Morales La Madrid; Sabine Mueller; Angel M Carcaboso; Fernando Carceller; Chris Jones
Journal:  Cancer Discov       Date:  2021-09-22       Impact factor: 39.397

3.  A model for an undergraduate research experience program in quantitative sciences.

Authors:  Kay See Tan; Elena B Elkin; Jaya M Satagopan
Journal:  J Stat Data Sci Educ       Date:  2022-02-22

4.  Machine Learning Prediction of Allosteric Drug Activity from Molecular Dynamics.

Authors:  Filippo Marchetti; Elisabetta Moroni; Alessandro Pandini; Giorgio Colombo
Journal:  J Phys Chem Lett       Date:  2021-04-12       Impact factor: 6.475

5.  Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.

Authors:  Wenjie Zhou; Junqing Li; Xiaofang Lu; Fangjie Liu; Tailai An; Xing Xiao; Zi Chong Kuo; Wenhui Wu; Yulong He
Journal:  Front Oncol       Date:  2021-02-25       Impact factor: 6.244

6.  AI delivers Michaelis constants as fuel for genome-scale metabolic models.

Authors:  Albert A Antolin; Marta Cascante
Journal:  PLoS Biol       Date:  2021-10-20       Impact factor: 8.029

7.  Evolution of kinase polypharmacology across HSP90 drug discovery.

Authors:  Albert A Antolin; Paul A Clarke; Ian Collins; Paul Workman; Bissan Al-Lazikani
Journal:  Cell Chem Biol       Date:  2021-06-01       Impact factor: 8.116
  7 in total

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