| Literature DB >> 31284781 |
Qian Tang1, Hu Ouyang1, Dongxiu He1,2, Cuiyun Yu1,2, Guotao Tang1,2.
Abstract
Triple-negative breast cancer (TNBC) is a distinct subtype of breast cancer characterized by high recurrence rates and poor prognosis compared to other breast cancers. MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of various post-transcriptional gene and silence a broad set of target genes. Many recent studies have demonstrated that miRNAs play an important role in the initiation, promotion, malignant conversion, progression, and metastasis of TNBC. Therefore, the aim of this review is to focus on recent advancements of microRNAs-based potential applications in diagnosis, treatment and prognosis of triple-negative breast cancer.Entities:
Keywords: Diagnosis; microRNA; prognosis; treatment; triple-negative breast cancer
Year: 2019 PMID: 31284781 DOI: 10.1080/21691401.2019.1638791
Source DB: PubMed Journal: Artif Cells Nanomed Biotechnol ISSN: 2169-1401 Impact factor: 5.678