Literature DB >> 31282548

Lipomatous Tumors in Pediatric Patients: A Retrospective Analysis of 50 cases.

Mine Özşen1, Ulviye Yalçinkaya, Zeynep Yazici, Mehmet Bartu Sarisözen.   

Abstract

OBJECTIVE: Although lipomatous tumors are the most common type of mesenchymal tumors in adults, they account for less than 10% of all soft tissue lesions in pediatric patients. In this descriptive study, we aim to present our series of pediatric lipomatous tumors consisting of lipoma, neural fibrolipoma, lipoblastoma, atypical lipomatous tumor, myxoid liposarcoma and pleomorphic liposarcoma, and to evaluate the clinicopathological characteristics of these tumors in reference to the literature. MATERIAL AND
METHOD: In this study, pediatric lipomatous tumor cases diagnosed between 2002 and 2018 were screened from pathological archives and retrospectively evaluated.
RESULTS: A total of 50 cases were diagnosed with lipomatous tumor within the mentioned period. Of the total cases, 24 were female (48%) and 26 were male (52%), with age distribution ranging from 1 to 204 months. Histopathological examination revealed lipoma in 26 cases (52%), lipoblastoma in 19 (38%), atypical lipomatous tumor in 2 (4%), myxoid liposarcoma in 2 (4%), and pleomorphic liposarcoma in 1 case (2%).
CONCLUSION: Although lipomatous tumors are the most common type of mesenchymal tumors; they rarely occur in children. Since there is a limited number of studies on pediatric lipomatous tumors in the literature, there is insufficient data on the prevalence and incidence of these tumors. These tumors may slowly enlarge to greater sizes, especially those localized in deep tissues, and may cause various clinical symptoms by compressing surrounding tissues. Local recurrences may occur, even after total excision, and require close monitoring.

Entities:  

Year:  2019        PMID: 31282548     DOI: 10.5146/tjpath.2019.01464

Source DB:  PubMed          Journal:  Turk Patoloji Derg        ISSN: 1018-5615


  4 in total

1.  Liposarcoma in children and young adults: a clinicopathologic and molecular study of 23 cases in one of the largest institutions of China.

Authors:  Ran Peng; Nan Li; Ting Lan; Huijiao Chen; Tianhai Du; Xin He; Min Chen; You Xie; Zhang Zhang; Wei Zhao; Hongying Zhang
Journal:  Virchows Arch       Date:  2021-03-18       Impact factor: 4.064

Review 2.  Recent Advancement in Atypical Lipomatous Tumor Research.

Authors:  Emi Mashima; Yu Sawada; Motonobu Nakamura
Journal:  Int J Mol Sci       Date:  2021-01-20       Impact factor: 5.923

Review 3.  Update of Pediatric Lipomatous Lesions: A Clinicopathological, Immunohistochemical and Molecular Overview.

Authors:  Eline Ameloot; Fleur Cordier; Jo Van Dorpe; David Creytens
Journal:  J Clin Med       Date:  2022-03-31       Impact factor: 4.241

Review 4.  Lipoblastoma of scalp in a 4-month-old patient: an extremely rare case report and review of the literature.

Authors:  Fatih Demir; Sait Öztürk; Hilal Balta; Fatih Serhat Erol
Journal:  Childs Nerv Syst       Date:  2021-08-09       Impact factor: 1.532

  4 in total

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