Zhizhou Duan1, Yuanyuan Wang2, Ye Tao3, Joanne L Bower2, Renjie Yu4, Shuilan Wang4, Zhengyan Wu4, Yongliang Lv4, Xiaonan Yang4, Xiaohong Li3, Liming Huang3, Ling Ma3, Qin Dong3, Jue Sun5, Shun Li5, Yong Yang6, Yuan Yang7, Ke Peng8, Runsen Chen9. 1. Suzhou Guangji Hospital, Affiliated Guangji Hospital of Soochow University, Soochow University, Suzhou, 215137, China; School of Health Sciences, Wuhan University, Wuhan, Hubei Province, 430072, China. 2. Division of Psychology, Faculty of Health and Life Sciences, De Montfort University, Leicester, LE1 9BH, UK. 3. Suzhou Science & Technology Town Hospital, Suzhou, Jiangsu Province, 215153, China. 4. Suzhou Guangji Hospital, Affiliated Guangji Hospital of Soochow University, Soochow University, Suzhou, 215137, China. 5. District Wumenqiao Street Canglang Xincheng Community Health Service Center, Jiangsu Pronvince, 215137, China. 6. Suzhou Guangji Hospital, Affiliated Guangji Hospital of Soochow University, Soochow University, Suzhou, 215137, China. Electronic address: szgjyy@126.com. 7. Department of Psychiatry, Southern Medical University Nanfang Hospital, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brian Science and Brain-Inspired Intelligence, Guangzhou, Guangdong, 510515, China. 8. The George Institute for Global Health, UNSW, Sydney, NSW2042, Australia; School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia. 9. The National Clinical Research Center for Mental Disorders, Beijing Key Laboratory of Mental Disorders & Advanced Innovation Center for Human Brain Protection, Beijing Anding Hospital, Capital Medical University, Beijing, 100088, China; Department of Psychiatry, University of Oxford, Oxford, OX3 7JX, UK. Electronic address: runsen.chen@psych.ox.ac.uk.
Abstract
BACKGROUND: Suicidal ideation is a common phenomenon among postpartum women around the world. However, evidence of the relationship between neuroticism and suicidal ideation among postpartum women is still lacking. METHODS: From March 2017 to December 2018, a total of 1027 postpartum women (assessed no later than one month post-birth) were recruited to complete questionnaires assessing neuroticism, depression, anxiety and suicidal ideation. RESULTS: Anxiety and depression fully mediated the association between neuroticism and suicidal ideation (Total indirect effects = 0.11, 95%CI: 0.07, 0.15). The indirect effect of the pathway of EPQ (Neuroticism)-Anxiety-Suicidal ideation was more significant than other pathways (Indirect effects=0.04, 95%CI: 0.02, 0.07). CONCLUSION: Interventions for suicidal ideation in postpartum women need to target neuroticism and further research is necessary understand the mechanisms by which neuroticism affects suicidal ideation.
BACKGROUND: Suicidal ideation is a common phenomenon among postpartum women around the world. However, evidence of the relationship between neuroticism and suicidal ideation among postpartum women is still lacking. METHODS: From March 2017 to December 2018, a total of 1027 postpartum women (assessed no later than one month post-birth) were recruited to complete questionnaires assessing neuroticism, depression, anxiety and suicidal ideation. RESULTS:Anxiety and depression fully mediated the association between neuroticism and suicidal ideation (Total indirect effects = 0.11, 95%CI: 0.07, 0.15). The indirect effect of the pathway of EPQ (Neuroticism)-Anxiety-Suicidal ideation was more significant than other pathways (Indirect effects=0.04, 95%CI: 0.02, 0.07). CONCLUSION: Interventions for suicidal ideation in postpartum women need to target neuroticism and further research is necessary understand the mechanisms by which neuroticism affects suicidal ideation.