Literature DB >> 31278210

Early-Onset Sepsis Risk Calculator Integration Into an Electronic Health Record in the Nursery.

Carole H Stipelman1, Elizabeth R Smith2, Margarita Diaz-Ochu2, Jennifer Spackman3, Greg Stoddard4, Kensaku Kawamoto5, Julie H Shakib2.   

Abstract

BACKGROUND AND OBJECTIVES: An early-onset sepsis (EOS) risk calculator tool to guide evaluation and treatment of infants at risk for sepsis has reduced antibiotic use without increased adverse outcomes. We performed an electronic health record (EHR)-driven quality improvement intervention to increase calculator use for infants admitted to a newborn nursery and reduce antibiotic treatment of infants at low risk for sepsis.
METHODS: This 2-phase intervention included programming (1) an EHR form containing calculator fields that were external to the infant's admission note, with nonautomatic access to the calculator, education for end-users, and reviewing risk scores in structured bedside rounds and (2) discrete data entry elements into the EHR admission form with a hyperlink to the calculator Web site. We used statistical process control to assess weekly entry of risk scores and antibiotic orders and interrupted time series to assess trend of antibiotic orders.
RESULTS: During phase 1 (duration, 14 months), a mean 59% of infants had EOS calculator scores entered. There was wide variability around the mean, with frequent crossing of weekly means beyond the 3σ control lines, indicating special-cause variation. During phase 2 (duration, 2 years), mean frequency of EOS calculator use increased to 85% of infants, and variability around the mean was within the 3σ control lines. The frequency of antibiotic orders decreased from preintervention (7%) to the final 6 months of phase 2 (1%, P < .001).
CONCLUSIONS: An EHR-driven quality improvement intervention increased EOS calculator use and reduced antibiotic orders, with no increase in adverse events.
Copyright © 2019 by the American Academy of Pediatrics.

Entities:  

Year:  2019        PMID: 31278210     DOI: 10.1542/peds.2018-3464

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  7 in total

1.  Special Commentary: Using Clinical Decision Support Systems to Bring Predictive Models to the Glaucoma Clinic.

Authors:  Brian C Stagg; Joshua D Stein; Felipe A Medeiros; Barbara Wirostko; Alan Crandall; M Elizabeth Hartnett; Mollie Cummins; Alan Morris; Rachel Hess; Kensaku Kawamoto
Journal:  Ophthalmol Glaucoma       Date:  2020-08-15

2.  Impact of Integrating a Neonatal Early-Onset Sepsis Risk Calculator into the Electronic Health Record.

Authors:  Nyles T Fowler; Michael Garcia; Cynthia Hankins
Journal:  Pediatr Qual Saf       Date:  2019-11-06

Review 3.  Relevance of Biomarkers Currently in Use or Research for Practical Diagnosis Approach of Neonatal Early-Onset Sepsis.

Authors:  Maura-Adelina Hincu; Gabriela-Ildiko Zonda; Gabriela Dumitrita Stanciu; Dragos Nemescu; Luminita Paduraru
Journal:  Children (Basel)       Date:  2020-12-20

4.  Early-onset sepsis risk calculator: a review of its effectiveness and comparative study with our evidence-based local guidelines.

Authors:  Gianluigi Laccetta; Massimiliano Ciantelli; Cristina Tuoni; Emilio Sigali; Mario Miccoli; Armando Cuttano
Journal:  Ital J Pediatr       Date:  2021-03-25       Impact factor: 2.638

5.  The impact of recency and adequacy of historical information on sepsis predictions using machine learning.

Authors:  Manaf Zargoush; Alireza Sameh; Mahdi Javadi; Siyavash Shabani; Somayeh Ghazalbash; Dan Perri
Journal:  Sci Rep       Date:  2021-10-21       Impact factor: 4.379

Review 6.  Computerized Clinical Decision Support Systems for the Early Detection of Sepsis Among Pediatric, Neonatal, and Maternal Inpatients: Scoping Review.

Authors:  Khalia Ackermann; Jannah Baker; Marino Festa; Brendan McMullan; Johanna Westbrook; Ling Li
Journal:  JMIR Med Inform       Date:  2022-05-06

7.  Sensitivity of the Kaiser Permanente early-onset sepsis calculator: A systematic review and meta-analysis.

Authors:  Katherine J Pettinger; Katie Mayers; Liz McKechnie; Bob Phillips
Journal:  EClinicalMedicine       Date:  2019-12-22
  7 in total

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