Literature DB >> 31277762

Assisted reproductive technology strategies in uterus transplantation.

Dominique de Ziegler1, Paul Pirtea2, Marie Carbonnel2, Marine Poulain2, Jean Marc Ayoubi2.   

Abstract

The development of assisted reproductive technology (ART) through four decades has led to offer the ultimate treatment for nearly all forms of infertility. The only remaining factor of childlessness however that still eludes ART and its routine variants are the absolute uterine infertility factors, for which the only option is an experimental approach, uterus transplantation. Progresses has been made over the past few years, and more are underway for simplifying the process notably for simplifying the uterus extraction step performed in the uterus donor. Furthermore, as the technique is being better mastered, the original indications for uterus transplantation, the congenital or acquired absence of the uterus, are now widened to also include incurable uterine fibrosis, or Asherman's syndrome. The ART-related practicalities of uterus transplantation, ovarian stimulation and uterine priming are being discussed in the present review.
Copyright © 2019 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Uterus transplantation; endometrial receptivity; hormonal replacement; implantation rates

Mesh:

Year:  2019        PMID: 31277762     DOI: 10.1016/j.fertnstert.2019.05.028

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  1 in total

1.  Recurrent implantation failure might be overestimated without PGT-A.

Authors:  Mauro Cozzolino
Journal:  Arch Gynecol Obstet       Date:  2020-09-01       Impact factor: 2.344

  1 in total

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