| Literature DB >> 31277747 |
Abstract
Methotrexate (MTX) is widely used in the treatment of psoriatic arthritis (PsA), despite the evidence base for this being limited. This narrative review summarizes the evidence to date of using MTX within different domains of psoriatic disease, including peripheral arthritis, axial disease, dactylitis, enthesitis, psoriasis, and nail disease. We also explore the role of MTX in combination therapy with tumor necrosis factor inhibitors, in addition to its safety and tolerability, to answer the question: should methotrexate have any place in the treatment of psoriatic arthritis?Entities:
Keywords: Efficacy; Methotrexate; Psoriasis; Psoriatic arthritis; Treatment
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Year: 2019 PMID： 31277747 DOI： 10.1016/j.rdc.2019.04.007
Source DB: PubMed Journal: Rheum Dis Clin North Am ISSN： 0889-857X Impact factor: 2.670