Georgios Sidiras1, Irini Patsaki1, Eleftherios Karatzanos2, Maria Dakoutrou3, Alexandros Kouvarakos1, Georgios Mitsiou3, Christina Routsi1, Georgios Stranjalis4, Serafim Nanas1, Vasiliki Gerovasili1. 1. First Critical Care Department, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece. 2. Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, First Critical Care Department, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece. Electronic address: lkaratzanos@gmail.com. 3. Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, First Critical Care Department, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece. 4. Department of Neurosurgery, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, Greece.
Abstract
PURPOSE: ICU acquired Weakness (ICUaW) is a common complication of critical illness. The aim of our study was the assessment of quality of life (QoL) and functional ability of patients with ICUaW, 6 months post hospital discharge. MATERIAL AND METHODS: Eight hundred seventy eight consecutive patients who had been discharged from the ICU were evaluated and 128 of them, 36 with ICUaW, were eligible for the study. Muscle strength was evaluated with MRC and Hand grip dynamometry. The Functional Independence Measure (FIM) was used to evaluate the functional ability while QoL was assessed with the Nottingham Health Profile and with the SF-36 questionnaire. RESULTS: Patients with ICUaW continued to have low MRC at hospital discharge, [53(49-56) vs. 59(58-60), p < 0.05]. Patients who developed ICUaW had lower Hand grip dynamometry at ICU, hospital discharge and 6 months after (p < 0.05). Patients with ICUaW have significantly lower FIM score at hospital discharge, 3 and 6 months post hospital discharge (p < 0.05) and persistently lower QoL at 3 and 6 months post hospital discharge(p < 0.05). CONCLUSIONS: ICUaW is associated with persistent deficiencies in functional ability and Qol leading to a prolonged period of recovery. Further research is needed in the field of prevention and targeted rehabilitation of functionality in this patient group.
PURPOSE:ICU acquired Weakness (ICUaW) is a common complication of critical illness. The aim of our study was the assessment of quality of life (QoL) and functional ability of patients with ICUaW, 6 months post hospital discharge. MATERIAL AND METHODS: Eight hundred seventy eight consecutive patients who had been discharged from the ICU were evaluated and 128 of them, 36 with ICUaW, were eligible for the study. Muscle strength was evaluated with MRC and Hand grip dynamometry. The Functional Independence Measure (FIM) was used to evaluate the functional ability while QoL was assessed with the Nottingham Health Profile and with the SF-36 questionnaire. RESULTS:Patients with ICUaW continued to have low MRC at hospital discharge, [53(49-56) vs. 59(58-60), p < 0.05]. Patients who developed ICUaW had lower Hand grip dynamometry at ICU, hospital discharge and 6 months after (p < 0.05). Patients with ICUaW have significantly lower FIM score at hospital discharge, 3 and 6 months post hospital discharge (p < 0.05) and persistently lower QoL at 3 and 6 months post hospital discharge(p < 0.05). CONCLUSIONS: ICUaW is associated with persistent deficiencies in functional ability and Qol leading to a prolonged period of recovery. Further research is needed in the field of prevention and targeted rehabilitation of functionality in this patient group.
Authors: Sabrina Eggmann; Gere Luder; Martin L Verra; Irina Irincheeva; Caroline H G Bastiaenen; Stephan M Jakob Journal: PLoS One Date: 2020-03-04 Impact factor: 3.240