Morus alba (mulberry), a natural potent compound in management of obesity.

Obesity is defined as body mass index, higher than 30 kg/m2, which are associated with diverse diseases including type 2 diabetes, hypertension, coronary diseases, certain cancers, osteoarthritis and dyslipidemia. The subject of this review article was to evaluate the potency of Morus alba or "mulberry" as natural potent anti-obesity agent in management of obesity. For writing this manuscript, we searched in all accessible international databases, electronic resources (PubMed, Science Direct, Springer, Wiley and Google), unpublished data (R&D reports, thesis and dissertation). The inhibitory effects of mulberry on digestive enzymes and adipocyte differentiation, and its stimulatory effects on energy expenditures, and lipid metabolism are responsible mechanisms for management of obesity in obese patients. Furthermore, the results of these preclinical studies and its related mechanisms should be evaluated in large clinical trials.