Rosa Dolz-Marco1,2,3, Ananda Kalevar4,5, H Richard McDonald4,5, Emmett T Cunningham4,5,6,7, K Bailey Freund1,2,8,9. 1. Unit of Macula, Oftalvist Clinic, Valencia, Spain. 2. Vitreous, Retina, Macula Consultants of New York, New York, New York. 3. LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York. 4. West Coast Retina Medical Group, San Francisco, California. 5. Department of Ophthalmology, California Pacific Medical Center, San Francisco, California. 6. Francis I. Proctor Foundation, University of California San Francisco, San Francisco, California. 7. Department of Ophthalmology, Stanford University School of Medicine, Stanford, California. 8. Department of Ophthalmology, Edward S Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; and. 9. Department of Ophthalmology, New York University School of Medicine, New York, New York.
Abstract
PURPOSE: To describe three patients with idiopathic multifocal choroiditis (MFC) who showed foci of foveal outer retinal hyperreflectivity on optical coherence tomography. METHODS: Retrospective review of electronic health records and multimodal imaging from three patients with MFC. RESULTS: Three consecutive white patients with MFC (two male and one female) presented with unilateral foveal outer retinal hyperreflectivity in the eye with active MFC. In all cases, the lesions persisted for at least 1 month. Optical coherence tomography demonstrated finger-like projections of hyperreflectivity extending from the retinal pigment epithelium and through disrupted interdigitation and ellipsoid zones into the outer nuclear layer, with some aspects of the lesions reaching the inner limiting membrane. Visual recovery varied in the three affected eyes. CONCLUSION: Foveal outer retinal hyperreflectivity is a novel optical coherence tomography finding in eyes with active MFC. Additional studies will be required to address the prevalence and prognostic importance of foveal outer retinal hyperreflectivity.
PURPOSE: To describe three patients with idiopathic multifocal choroiditis (MFC) who showed foci of foveal outer retinal hyperreflectivity on optical coherence tomography. METHODS: Retrospective review of electronic health records and multimodal imaging from three patients with MFC. RESULTS: Three consecutive white patients with MFC (two male and one female) presented with unilateral foveal outer retinal hyperreflectivity in the eye with active MFC. In all cases, the lesions persisted for at least 1 month. Optical coherence tomography demonstrated finger-like projections of hyperreflectivity extending from the retinal pigment epithelium and through disrupted interdigitation and ellipsoid zones into the outer nuclear layer, with some aspects of the lesions reaching the inner limiting membrane. Visual recovery varied in the three affected eyes. CONCLUSION: Foveal outer retinal hyperreflectivity is a novel optical coherence tomography finding in eyes with active MFC. Additional studies will be required to address the prevalence and prognostic importance of foveal outer retinal hyperreflectivity.