| Literature DB >> 31273880 |
Karl Landheer1, Rolf F Schulte2, Michael S Treacy1, Kelley M Swanberg1, Christoph Juchem1,3.
Abstract
This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent pulse sequence diagram, and theoretical concepts of the measured signal are given for five spatial localization sequences and three modules designed to increase metabolic specificity. Cross-sequence comparisons, including potential modifications for estimating quantitative measures like spin-lattice relaxation time T1 , spin-spin relaxation time T2 , and diffusion coefficients are briefly discussed. Level of Evidence: 5 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2020;51:1008-1029.Entities:
Keywords: zzm321990J-editing; 2D spectroscopy; MQF; MRS; pulse sequences
Mesh:
Year: 2019 PMID: 31273880 DOI: 10.1002/jmri.26846
Source DB: PubMed Journal: J Magn Reson Imaging ISSN: 1053-1807 Impact factor: 4.813