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Literature DB >> 3127383

The Escherichia coli K-12 lexA2 gene encodes a hypocleavable repressor.

Abstract

LexA2 repressor was partially inactivated after mitomycin C or UV light treatment in a recA+ or recA85(Prtc) (protease constitutive) host background. LexA2 protein was cleaved, but the reaction was slower than that observed for LexA+ repressor. lexA2 had a C-to-T transition at nucleotide 461 (Thr-154 to Ile).

Entities: Chemical Mutation Species

Mesh：

Substances：

Year: 1988 PMID： 3127383 PMCID： PMC211063 DOI： 10.1128/jb.170.4.1975-1977.1988

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

14 in total

1. Identification of the lexA gene product of Escherichia coli K-12.

Authors: J W Little; J E Harper
Journal: Proc Natl Acad Sci U S A Date: 1979-12 Impact factor: 11.205

2. Differential repression of SOS genes by unstable lexA41 (tsl-1) protein causes a "split-phenotype" in Escherichia coli K-12.

Authors: K R Peterson; D W Mount
Journal: J Mol Biol Date: 1987-01-05 Impact factor: 5.469

3. Nucleotide sequence of the lexA gene of Escherichia coli K-12.

Authors: B E Markham; J W Little; D W Mount
Journal: Nucleic Acids Res Date: 1981-08-25 Impact factor: 16.971

4. The SOS regulatory system: control of its state by the level of RecA protease.

Authors: J W Little
Journal: J Mol Biol Date: 1983-07-15 Impact factor: 5.469

5. The lexA gene product represses its own promoter.

Authors: R Brent; M Ptashne
Journal: Proc Natl Acad Sci U S A Date: 1980-04 Impact factor: 11.205

6. Mechanism of action of the lexA gene product.

Authors: R Brent; M Ptashne
Journal: Proc Natl Acad Sci U S A Date: 1981-07 Impact factor: 11.205

7. Dominant mutations (lex) in Escherichia coli K-12 which affect radiation sensitivity and frequency of ultraviolet lght-induced mutations.

Authors: D W Mount; K B Low; S J Edmiston
Journal: J Bacteriol Date: 1972-11 Impact factor: 3.490

8. A mutant of Escherichia coli showing constitutive expression of the lysogenic induction and error-prone DNA repair pathways.

Authors: D W Mount
Journal: Proc Natl Acad Sci U S A Date: 1977-01 Impact factor: 11.205

2. Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressor.

Authors: L K Lewis; M E Jenkins; D W Mount
Journal: J Bacteriol Date: 1992-05 Impact factor: 3.490

2 in total