Literature DB >> 31273600

(Mammary Analogue) Secretory Carcinoma of the Nasal Cavity: Report of a Rare Case with p63 and DOG1 Expression and Uncommon Exon 4-Exon 14 ETV6-NTRK3 Fusion Diagnosed with Next Generation Sequencing.

Bingcheng Wu1, Thomas Kwok Seng Loh2, Tomas Vanecek3, Michal Michal3,4, Fredrik Petersson5.   

Abstract

We present a 72 years old male with a left nasal cavity (mammary analogue) secretory carcinoma (SC) which exhibited classical morphological features on light microscopical examination, diffuse strong S100 and mammoglobin positivity on immunohistochemistry, and ETV6-NTRK3 gene fusion on next generation sequencing (NGS) analysis. Unusual features of this tumor are expression of p63 and DOG1 on immunohistochemistry and the atypical junction between Exon 4 of the ETV6 gene and Exon 14 of the NTRK3 gene.

Entities:  

Keywords:  ETV6-NTRK3 fusion protein, human; Immunohistochemistry; Mammary analogue secretory carcinoma; Nasal cavity

Mesh:

Substances:

Year:  2019        PMID: 31273600      PMCID: PMC7235099          DOI: 10.1007/s12105-019-01051-z

Source DB:  PubMed          Journal:  Head Neck Pathol        ISSN: 1936-055X


  28 in total

1.  Mammary analogue secretory carcinoma of the sinus ethmoidalis.

Authors:  Eveline Lurquin; Mark Jorissen; Maria Debiec-Rychter; Robert Hermans; Esther Hauben
Journal:  Histopathology       Date:  2015-05-12       Impact factor: 5.087

2.  Salivary Secretory Carcinoma With a Novel ETV6-MET Fusion: Expanding the Molecular Spectrum of a Recently Described Entity.

Authors:  Lisa M Rooper; Theodoros Karantanos; Yi Ning; Justin A Bishop; Sarah W Gordon; Hyunseok Kang
Journal:  Am J Surg Pathol       Date:  2018-08       Impact factor: 6.394

3.  Mammary Analog Secretory Carcinoma With ETV6 Rearrangement Arising in the Conjunctiva and Eyelid.

Authors:  Yongyang Bao; Jiang Li; Yanbo Zhu
Journal:  Am J Dermatopathol       Date:  2018-07       Impact factor: 1.533

4.  Primary Cutaneous Mammary Analog Secretory Carcinoma With ETV6-NTRK3 Translocation.

Authors:  Sapna M Amin; Adam Beattie; Xia Ling; Lawrence J Jennings; Joan Guitart
Journal:  Am J Dermatopathol       Date:  2016-11       Impact factor: 1.533

5.  Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity.

Authors:  Alena Skálová; Tomas Vanecek; Radek Sima; Jan Laco; Ilan Weinreb; Bayardo Perez-Ordonez; Ivo Starek; Marie Geierova; Roderrick H W Simpson; Fabricio Passador-Santos; Ales Ryska; Ilmo Leivo; Zdenek Kinkor; Michal Michal
Journal:  Am J Surg Pathol       Date:  2010-05       Impact factor: 6.394

6.  Mammary Analog Secretory Carcinoma of the Nasal Cavity: Characterization of 2 Cases and Their Distinction From Other Low-grade Sinonasal Adenocarcinomas.

Authors:  Martina Baneckova; Abbas Agaimy; Simon Andreasen; Tomas Vanecek; Petr Steiner; David Slouka; Tomas Svoboda; Marketa Miesbauerova; Michael Michal; Alena Skálová
Journal:  Am J Surg Pathol       Date:  2018-06       Impact factor: 6.394

7.  Mammary analog secretory carcinoma of salivary glands: a report of 2 cases with expression of basal/myoepithelial markers (calponin, CD10 and p63 protein).

Authors:  Jan Laco; Marián Švajdler; Jan Andrejs; Dušan Hrubala; Mária Hácová; Tomáš Vaněček; Alena Skálová; Aleš Ryška
Journal:  Pathol Res Pract       Date:  2013-01-26       Impact factor: 3.250

8.  Primary mammary analogue secretory carcinoma of the lung: a case report.

Authors:  Tao Huang; Jonathan B McHugh; Gerald J Berry; Jeffrey L Myers
Journal:  Hum Pathol       Date:  2017-11-02       Impact factor: 3.466

Review 9.  Secretory Carcinoma of the Thyroid Gland: Report of a Highly Aggressive Case Clinically Mimicking Undifferentiated Carcinoma and Review of the Literature.

Authors:  Megan A Desai; Mitra Mehrad; Kim A Ely; Justin A Bishop; James Netterville; Joseph M Aulino; James S Lewis
Journal:  Head Neck Pathol       Date:  2018-12-18

10.  Characterisation of DOG-1 Expression in Salivary Gland Tumours and Comparison with Myoepithelial Markers.

Authors:  Syed A Khurram; Paul M Speight
Journal:  Head Neck Pathol       Date:  2018-04-18
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  1 in total

1.  Characterization of an ETV6-NTRK3 rearrangement with unusual, but highly significant FISH signal pattern in a secretory carcinoma of the salivary gland: a case report.

Authors:  Florian Wagner; Ralf Greim; Kathrin Krebs; Finn Luebben; Arno Dimmler
Journal:  Diagn Pathol       Date:  2021-08-09       Impact factor: 2.644

  1 in total

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