| Literature DB >> 31273600 |
Bingcheng Wu1, Thomas Kwok Seng Loh2, Tomas Vanecek3, Michal Michal3,4, Fredrik Petersson5.
Abstract
We present a 72 years old male with a left nasal cavity (mammary analogue) secretory carcinoma (SC) which exhibited classical morphological features on light microscopical examination, diffuse strong S100 and mammoglobin positivity on immunohistochemistry, and ETV6-NTRK3 gene fusion on next generation sequencing (NGS) analysis. Unusual features of this tumor are expression of p63 and DOG1 on immunohistochemistry and the atypical junction between Exon 4 of the ETV6 gene and Exon 14 of the NTRK3 gene.Entities:
Keywords: ETV6-NTRK3 fusion protein, human; Immunohistochemistry; Mammary analogue secretory carcinoma; Nasal cavity
Mesh:
Substances:
Year: 2019 PMID: 31273600 PMCID: PMC7235099 DOI: 10.1007/s12105-019-01051-z
Source DB: PubMed Journal: Head Neck Pathol ISSN: 1936-055X