Literature DB >> 3127329

Lymphokine-induced MHC class II antigen expression on cultured retinal pigment epithelial cells and the influence of cyclosporin A.

J Liversidge1, H F Sewell, A W Thomson, J V Forrester.   

Abstract

Culture of rat or guinea-pig retinal pigment epithelium (RPE) cells with Con A-induced lymphokine derived from splenic lymphocytes or rat recombinant IFN-gamma induces strong MHC class II (Ia) antigen expression on up to 40% of RPE cells. Cyclosporin A, which inhibits intravitreal inflammation and Ia antigen expression on RPE cells in vivo, despite a choroidal T-cell infiltrate, suppresses production of Ia-inducing lymphokine but does not suppress in vitro responses of RPE cells to preformed lymphokine.

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Year:  1988        PMID： 3127329      PMCID： PMC1454508     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  29 in total

1.  Induction of class II (Ia) alloantigen expression on corneal endothelium in vivo and in vitro.

Authors:  J J Donnelly; W Y Li; J H Rockey; R A Prendergast
Journal:  Invest Ophthalmol Vis Sci       Date:  1985-04       Impact factor: 4.799

2.  Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

Authors:  J L Cordell; B Falini; W N Erber; A K Ghosh; Z Abdulaziz; S MacDonald; K A Pulford; H Stein; D Y Mason
Journal:  J Histochem Cytochem       Date:  1984-02       Impact factor: 2.479

3.  Production of monoclonal antibodies defining guinea pig T-cell surface markers and a strain 13 Ia-like antigen: the value of immunohistological screening.

Authors:  B T Tan; F Ekelaar; J Luirink; G Rimmelzwaan; A J De Jonge; R J Scheper
Journal:  Hybridoma       Date:  1985

4.  Local production of Ia-inducing activity in experimental immunogenic uveitis.

Authors:  J J Donnelly; R A Prendergast
Journal:  Cell Immunol       Date:  1984-07       Impact factor: 4.868

5.  Expression of class II antigen in endotoxin induced uveitis.

Authors:  M K Kim; A G Palestine; R B Nussenblatt; C C Chan
Journal:  Curr Eye Res       Date:  1986-11       Impact factor: 2.424

6.  Alpha-fetoprotein inhibits macrophage expression of Ia antigens.

Authors:  C Y Lu; P S Changelian; E R Unanue
Journal:  J Immunol       Date:  1984-04       Impact factor: 5.422

7.  Effects of cyclosporine and other immunosuppressive drugs on experimental autoimmune uveoretinitis in rats.

Authors:  M Mochizuki; R B Nussenblatt; T Kuwabara; I Gery
Journal:  Invest Ophthalmol Vis Sci       Date:  1985-02       Impact factor: 4.799

8.  In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis.

Authors:  G F Bottazzo; B M Dean; J M McNally; E H MacKay; P G Swift; D R Gamble
Journal:  N Engl J Med       Date:  1985-08-08       Impact factor: 91.245

9.  Class II antigen expression and gamma interferon modulation of monocytes and retinal pigment epithelial cells from patients with retinitis pigmentosa.

Authors:  B Detrick; D A Newsome; C M Percopo; J J Hooks
Journal:  Clin Immunol Immunopathol       Date:  1985-08

10.  Cyclosporin A inhibits lymphokine production but not the responses of macrophages to lymphokines.

Authors:  A W Thomson; D K Moon; C L Geczy; D S Nelson
Journal:  Immunology       Date:  1983-02       Impact factor: 7.397
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  14 in total

Review 1.  Basement membranes and artificial substrates in cell transplantation.

Authors:  Carl Sheridan; Rachel Williams; Ian Grierson
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-11-20       Impact factor: 3.117

2.  The expression of class I major histocompatibility antigens by human retinal pigment epithelium in vitro.

Authors:  M T Benson; L Shepherd; D Cottam; J Lawry; R C Rees; I G Rennie
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

3.  Interferon-gamma (IFN-gamma) production in vivo in experimental autoimmune uveoretinitis.

Authors:  D G Charteris; S L Lightman
Journal:  Immunology       Date:  1992-03       Impact factor: 7.397

4.  The influence of penetrating keratoplasty and cyclosporin A therapy on MHC class II (Ia)-positive cells in the rat iris and choroid.

Authors:  S E Coupland; L Krause; F Hoffmann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-02       Impact factor: 3.117

5.  The behaviour of ED1- and ED2-positive cells in the rat iris and choroid following penetrating keratoplasty and cyclosporin A therapy.

Authors:  L Krause; S E Coupland; F Hoffmann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-08       Impact factor: 3.117

Review 6.  The influence of cyclosporin A on cell-mediated immunity.

Authors:  A W Thomson; L M Webster
Journal:  Clin Exp Immunol       Date:  1988-03       Impact factor: 4.330

7.  Induction of MHC class II antigen in cultured bovine ciliary epithelial cells.

Authors:  H Helbig; R C Gurley; R J Reichl; R Mahdi; R B Nussenblatt; A G Palestine
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1990       Impact factor: 3.117

8.  Analysis of retinal pigment epithelium integrin expression and adhesion to aged submacular human Bruch's membrane.

Authors:  Marco A Zarbin
Journal:  Trans Am Ophthalmol Soc       Date:  2003

9.  Reactivation of uveitogenic T cells by retinal astrocytes derived from experimental autoimmune uveitis-prone B10RIII mice.

Authors:  Guomin Jiang; Yan Ke; Deming Sun; Gencheng Han; Henry J Kaplan; Hui Shao
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-01       Impact factor: 4.799

10.  Human retinal pigment epithelial cells differentially express MHC class II (HLA, DP, DR and DQ) antigens in response to in vitro stimulation with lymphokine or purified IFN-gamma.

Authors:  J M Liversidge; H F Sewell; J V Forrester
Journal:  Clin Exp Immunol       Date:  1988-09       Impact factor: 4.330
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