Literature DB >> 3127236

Suppression by LH-releasing hormone (LHRH) of the augmenting effect of estradiol on the secretion of LH and FSH by the rat pituitary gland.

G A Schuiling1, N Pols-Valkhof, T R Koiter.   

Abstract

Estradiol sensitizes the pituitary gland for the gonadotropin-releasing activity of LHRH. LHRH desensitizes the pituitary gland and does so in a dose-dependent manner. Moreover, LHRH dose-dependently suppresses the sensitizing effect of EB. In rats with an LHRH concentration in the plasma of about 90 pg/ml, the sensitizing effect of estradiol is absent.

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Year:  1988        PMID： 3127236     DOI： 10.1007/bf01941719

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Levels of follicle-stimulating hormone, luteinizing hormone, oestradiol-17 beta and progesterone, and follicular growth in the pseudopregnant rat.

Authors:  R Welschen; P Osman; J Dullaart; W J de Greef; J T Uilenbroek; F H de Jong
Journal:  J Endocrinol       Date:  1975-01       Impact factor: 4.286

2.  Production and characterization of an antiserum to synthetic gonadotropin-releasing hormone.

Authors:  Y Koch; M Wilchek; M Fridkin; P Chobsieng; U Zor; H R Lindner
Journal:  Biochem Biophys Res Commun       Date:  1973-12-10       Impact factor: 3.575

3.  Gonadotropin-releasing hormone surge in pro-oestrous rats.

Authors:  D K Sarkar; S A Chiappa; G Fink; N M Sherwood
Journal:  Nature       Date:  1976-12-02       Impact factor: 49.962

4.  Evidence for a periodic release of LH in castrated male and female rats.

Authors:  V L Gay; N A Sheth
Journal:  Endocrinology       Date:  1972-01       Impact factor: 4.736

5.  Site of origin of the pulsatile secretion of luteinizing hormone in long-term ovariectomized rats.

Authors:  G A Schuiling; H P Gnodde
Journal:  J Endocrinol       Date:  1976-07       Impact factor: 4.286

6.  Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone.

Authors:  P E Belchetz; T M Plant; Y Nakai; E J Keogh; E Knobil
Journal:  Science       Date:  1978-11-10       Impact factor: 47.728

7.  A comparison of the LH-releasing activities of LH-RH and its agonistic analogue buserelin in the ovariectomized rat.

Authors:  T R Koiter; G C van der Schaaf-Verdonk; H Kuiper; N Pols-Valkhof; G A Schuiling
Journal:  Life Sci       Date:  1984-04-16       Impact factor: 5.037

8.  Prolonged combined in vivo pre-treatment with luteinizing hormone-releasing hormone (LRH) and oestradiol benzoate causes long-lasting suppression of the autonomous and the LRH-stimulated secretion of luteinizing hormone and follicle stimulating hormone. An in vitro study.

Authors:  G A Schuiling; H Moes; T R Koiter
Journal:  Acta Endocrinol (Copenh)       Date:  1984-04

9.  Blockade of LH and FSH secretion by LH-releasing hormone, by the LH-releasing hormone analogue, buserelin, and by combined treatment with LH-releasing hormone and oestradiol benzoate.

Authors:  G A Schuiling; N Pols-Valkhof; G C van der Schaaf-Verdonk; T R Koiter
Journal:  J Endocrinol       Date:  1984-12       Impact factor: 4.286

10.  Luteinizing hormone releasing factor in pituitary stalk plasma from long-term ovariectomized rats: effects of steroids.

Authors:  D K Sarkar; G Fink
Journal:  J Endocrinol       Date:  1980-09       Impact factor: 4.286
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