Literature DB >> 31271755

Bursting Enables GRP Neurons to Engage Spinal Itch Circuits.

Hugues Petitjean1, Philippe Séguéla2, Reza Sharif-Naeini3.   

Abstract

In this issue of Neuron, Pagani et al. (2019) find that itch signaling occurs only when GRP neurons fire action potentials in bursts. This enables GRP release and the activation of GRPR neurons, which help carry the itch signal to the brain.
Copyright © 2019. Published by Elsevier Inc.

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Year:  2019        PMID： 31271755     DOI： 10.1016/j.neuron.2019.06.009

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  2 in total

1.  The cellular basis of protease-activated receptor 2-evoked mechanical and affective pain.

Authors:  Shayne N Hassler; Moeno Kume; Juliet M Mwirigi; Ayesha Ahmad; Stephanie Shiers; Andi Wangzhou; Pradipta R Ray; Serge N Belugin; Dhananjay K Naik; Michael D Burton; Josef Vagner; Scott Boitano; Armen N Akopian; Gregory Dussor; Theodore J Price
Journal:  JCI Insight       Date:  2020-06-04

2.  New Insight into the Origins of Itch and Pain: How are Itch and Pain Signals Coded and Discriminated by Primary Sensory Neurons?

Authors:  Yue Hu; Wen-Qi Shan; Bin Wu; Tong Liu
Journal:  Neurosci Bull       Date:  2021-03-08       Impact factor: 5.203
  2 in total

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