Lucie Wartique1, Yvan Jamilloux2,3, Audrey De Parisot De Bernecourt2,3, Laurent Kodjikian3,4, Hervé Ghesquieres3,5, Christophe Ide1, Pascal Sève2,3. 1. Department of Internal Medicine, Grand Hôpital de Charleroi , Charleroi, Belgium. 2. Department of Internal Medicine, Croix-Rousse University Hospital , Lyon, France. 3. Claude Bernard Lyon 1 University , Lyon, France. 4. Department of Ophthalmology, Croix-Rousse University Hospital , Lyon, France. 5. Department of Hematology, Lyon Sud University Hospital , Lyon, France.
Abstract
PURPOSE: The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis. MATERIAL AND METHODS: A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features. CONCLUSION: Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.
PURPOSE: The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis. MATERIAL AND METHODS: A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features. CONCLUSION: Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.
Entities:
Keywords:
Primary central nervous system lymphoma; primary vitreoretinal lymphoma; sarcoidosis; uveitis; vitrectomy