Hongliang Zou1, Jian Yang1. 1. Nanjing University of Science and Technology, P.R. China.
Abstract
Objective: The aim of this work is to explore the relationship between temporal variability and brain lateralization in ADHD. Method: The temporal variabilities of 116 brain regions based on resting-state functional magnetic resonance imaging (rs-fMRI) data were calculated for analysis. Results: Between-group comparison revealed that in comparison with the controls, ADHD participants showed significantly higher temporal variability in the left superior frontal gyrus (medial), left rectus gyrus, left inferior parietal lobule and angular gyrus, and lower temporal variability in the amygdala, left caudate and putamen. Besides, ADHD patients exhibited significantly increased leftward lateralization in the orbitofrontal cortex (inferior), and decreased rightward lateralization in the orbitofrontal cortex (medial) and rectus gyrus, compared with controls. Lateralization indices were also found to be related with clinical characteristics of ADHD patients. Conclusion: Our results may help us deeper in understanding the pathology of ADHD.
Objective: The aim of this work is to explore the relationship between temporal variability and brain lateralization in ADHD. Method: The temporal variabilities of 116 brain regions based on resting-state functional magnetic resonance imaging (rs-fMRI) data were calculated for analysis. Results: Between-group comparison revealed that in comparison with the controls, ADHDparticipants showed significantly higher temporal variability in the left superior frontal gyrus (medial), left rectus gyrus, left inferior parietal lobule and angular gyrus, and lower temporal variability in the amygdala, left caudate and putamen. Besides, ADHDpatients exhibited significantly increased leftward lateralization in the orbitofrontal cortex (inferior), and decreased rightward lateralization in the orbitofrontal cortex (medial) and rectus gyrus, compared with controls. Lateralization indices were also found to be related with clinical characteristics of ADHDpatients. Conclusion: Our results may help us deeper in understanding the pathology of ADHD.
Authors: Merel C Postema; Martine Hoogman; Sara Ambrosino; Philip Asherson; Tobias Banaschewski; Cibele E Bandeira; Alexandr Baranov; Claiton H D Bau; Sarah Baumeister; Ramona Baur-Streubel; Mark A Bellgrove; Joseph Biederman; Janita Bralten; Daniel Brandeis; Silvia Brem; Jan K Buitelaar; Geraldo F Busatto; Francisco X Castellanos; Mara Cercignani; Tiffany M Chaim-Avancini; Kaylita C Chantiluke; Anastasia Christakou; David Coghill; Annette Conzelmann; Ana I Cubillo; Renata B Cupertino; Patrick de Zeeuw; Alysa E Doyle; Sarah Durston; Eric A Earl; Jeffery N Epstein; Thomas Ethofer; Damien A Fair; Andreas J Fallgatter; Stephen V Faraone; Thomas Frodl; Matt C Gabel; Tinatin Gogberashvili; Eugenio H Grevet; Jan Haavik; Neil A Harrison; Catharina A Hartman; Dirk J Heslenfeld; Pieter J Hoekstra; Sarah Hohmann; Marie F Høvik; Terry L Jernigan; Bernd Kardatzki; Georgii Karkashadze; Clare Kelly; Gregor Kohls; Kerstin Konrad; Jonna Kuntsi; Luisa Lazaro; Sara Lera-Miguel; Klaus-Peter Lesch; Mario R Louza; Astri J Lundervold; Charles B Malpas; Paulo Mattos; Hazel McCarthy; Leyla Namazova-Baranova; Rosa Nicolau; Joel T Nigg; Stephanie E Novotny; Eileen Oberwelland Weiss; Ruth L O'Gorman Tuura; Jaap Oosterlaan; Bob Oranje; Yannis Paloyelis; Paul Pauli; Felipe A Picon; Kerstin J Plessen; J Antoni Ramos-Quiroga; Andreas Reif; Liesbeth Reneman; Pedro G P Rosa; Katya Rubia; Anouk Schrantee; Lizanne J S Schweren; Jochen Seitz; Philip Shaw; Tim J Silk; Norbert Skokauskas; Juan C Soliva Vila; Michael C Stevens; Gustavo Sudre; Leanne Tamm; Fernanda Tovar-Moll; Theo G M van Erp; Alasdair Vance; Oscar Vilarroya; Yolanda Vives-Gilabert; Georg G von Polier; Susanne Walitza; Yuliya N Yoncheva; Marcus V Zanetti; Georg C Ziegler; David C Glahn; Neda Jahanshad; Sarah E Medland; Paul M Thompson; Simon E Fisher; Barbara Franke; Clyde Francks Journal: J Child Psychol Psychiatry Date: 2021-03-22 Impact factor: 8.265
Authors: Zhiqiang Sha; Dick Schijven; Amaia Carrion-Castillo; Marc Joliot; Bernard Mazoyer; Simon E Fisher; Fabrice Crivello; Clyde Francks Journal: Nat Hum Behav Date: 2021-03-15