| Literature DB >> 31268107 |
Ana I Carbajo-Gordillo1, Julio Rodríguez-Lavado2, José Luis Jiménez Blanco2, Juan M Benito1, Christophe Di Giorgio3, Itziar Vélaz4, Concepción Tros de Ilarduya5, Carmen Ortiz Mellet2, José M García Fernández1.
Abstract
An original family of multivalent vectors encompassing gemini and facial amphiphilicity, namely cationic Siamese twin surfactants, has been prepared from the disaccharide trehalose; molecular engineering lets us modulate the self-assembling properties and the topology of the nanocomplexes with plasmid DNA for efficient gene delivery in vitro and in vivo.Entities:
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Year: 2019 PMID： 31268107 DOI： 10.1039/c9cc04489b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222