Literature DB >> 31268098

Stabilization of microtubules by encapsulation of the GFP using a Tau-derived peptide.

Hiroshi Inaba1, Takahisa Yamamoto2, Takashi Iwasaki3, Arif Md Rashedul Kabir4, Akira Kakugo5, Kazuki Sada5, Kazunori Matsuura1.   

Abstract

We constructed GFP-encapsulated microtubules (MTs) using a Tau-derived peptide which binds to their interior. The encapsulation of the GFP dramatically increased the rigidity of MTs, resulting in their enhanced velocity on a kinesin-coated substrate. Moreover, the GFP-encapsulated MTs were significantly more stable than normal MTs.

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Year:  2019        PMID： 31268098     DOI： 10.1039/c9cc04345d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Controlling the Rigidity of Kinesin-Propelled Microtubules in an In Vitro Gliding Assay Using the Deep-Sea Osmolyte Trimethylamine N-Oxide.

Authors:  Arif Md Rashedul Kabir; Tasrina Munmun; Tomohiko Hayashi; Satoshi Yasuda; Atsushi P Kimura; Masahiro Kinoshita; Takeshi Murata; Kazuki Sada; Akira Kakugo
Journal:  ACS Omega       Date:  2022-01-24

2.  Generation of stable microtubule superstructures by binding of peptide-fused tetrameric proteins to inside and outside.

Authors:  Hiroshi Inaba; Yurina Sueki; Muneyoshi Ichikawa; Arif Md Rashedul Kabir; Takashi Iwasaki; Hideki Shigematsu; Akira Kakugo; Kazuki Sada; Tomoya Tsukazaki; Kazunori Matsuura
Journal:  Sci Adv       Date:  2022-09-07       Impact factor: 14.957
  2 in total

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